SCHEMBL9973868

SCHEMBL9973868

Cc1ccccc1NC(=O)CCc1cccc(O)c1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.64
ALDH1A1 P00352 3/20 0.56
ALOX12 P18054 2/20 0.56
HPGD P15428 1/20 0.56
P2RX7 Q99572 1/20 0.55
HCAR2 Q8TDS4 4/20 0.54
HDAC3 O15379 1/20 0.54
HDAC4 P56524 1/20 0.54
HDAC1 Q13547 1/20 0.54
HDAC7 Q8WUI4 1/20 0.54
HDAC2 Q92769 1/20 0.54
HDAC10 Q969S8 1/20 0.54
HDAC11 Q96DB2 1/20 0.54
HDAC8 Q9BY41 1/20 0.54
HDAC6 Q9UBN7 1/20 0.54
HDAC9 Q9UKV0 1/20 0.54
HDAC5 Q9UQL6 1/20 0.54
KDM4E B2RXH2 1/20 0.52
LMNA P02545 1/20 0.52
RAB9A P51151 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9973870 0.89 LMNA (0.55) POLBALDH1A1P2RX7HCAR2HDAC6
SCHEMBL23886030 0.87 POLB (0.66) POLBALDH1A1ALOX12HPGDHCAR2
SCHEMBL14227346 0.86 GAA (0.61) POLBALDH1A1HPGDHDAC3HDAC4
SCHEMBL29844215 0.85 POLB (0.80) POLBALDH1A1ALOX12HPGDHDAC3
SCHEMBL8440269 0.85 POLB (0.80) POLBALDH1A1ALOX12HPGDHDAC3
SCHEMBL14227337 0.84 POLB (0.66) POLBALDH1A1ALOX12HPGDHCAR2
SCHEMBL14227341 0.83 POLB (0.57) POLBALDH1A1ALOX12HPGDHCAR2
SCHEMBL15177988 0.83 POLB (0.48) POLBALDH1A1ALOX12HPGDP2RX7
SCHEMBL14227338 0.83 HCAR2 (0.57) POLBALDH1A1ALOX12HPGDHCAR2
SCHEMBL6102348 0.83 HCAR2 (0.75) HCAR2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8409552-B2 Anthranillic acid amides and derivatives thereof as cosmetic and pharmaceutical active compounds SYMRISE AG (DE) 2013-04-02 US disclosed
US-20120315233-A1 ANTHRANILLIC ACID AMIDES AND DERIVATIVES THEREOF AS COSMETIC AND PHARMACEUTICAL ACTIVE COMPOUNDS SYMRISE AG (DE) 2012-12-13 US disclosed
US-8203016-B2 Anthranilic acid amides and derivatives thereof as cosmetic and pharmaceutical agents SYMRISE AG (DE) 2012-06-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120315233-A1 ANTHRANILLIC ACID AMIDES AND DERIVATIVES THEREOF AS COSMETIC AND PHARMACEUTICAL ACTIVE COMPOUNDS CMA1, TPSAB1, HRH1 POLB 3235/4885ALDH1A1 101/4885ALOX12 267/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.