SCHEMBL997398

SCHEMBL997398

CCC=CC(=O)OC(=O)O

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 6/20 0.37
FFAR3 O14843 1/20 0.35
MAPT P10636 4/20 0.34
ALDH1A1 P00352 4/20 0.34
OXER1 Q8TDS5 4/20 0.34
CYP19A1 P11511 2/20 0.34
RXRA P19793 2/20 0.34
PPARG P37231 2/20 0.34
FFAR1 O14842 1/20 0.34
PPARA Q07869 2/20 0.34
PTGS1 P23219 2/20 0.32
F7 P08709 2/20 0.32
F3 P13726 2/20 0.32
ADORA3 P0DMS8 1/20 0.32
KMT2A Q03164 1/20 0.32
PPARD Q03181 1/20 0.32
ATM Q13315 1/20 0.32
KEAP1 Q14145 1/20 0.31
NFE2L2 Q16236 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15710928 0.90 MAPT (0.39) HCAR2FFAR3MAPTALDH1A1OXER1
SCHEMBL15720749 0.90 MAPT (0.39) HCAR2FFAR3MAPTALDH1A1OXER1
SCHEMBL11443858 0.90 MAPT (0.39) HCAR2FFAR3MAPTALDH1A1OXER1
SCHEMBL13244979 0.81 MAPT (0.34) HCAR2MAPTALDH1A1OXER1CYP19A1
SCHEMBL3987452 0.81 ALDH1A1 (0.48) HCAR2MAPTALDH1A1OXER1CYP19A1
SCHEMBL27975047 0.81 MAPT (0.34) HCAR2MAPTALDH1A1OXER1CYP19A1
SCHEMBL11340584 0.79 TSHR (0.42) HCAR2MAPTALDH1A1ATM
SCHEMBL28429034 0.77 HCAR2 (0.31) HCAR2MAPTPPARA
SCHEMBL7568618 0.76 HCAR2 (0.42) HCAR2MAPTALDH1A1ATMKEAP1
SCHEMBL4838653 0.76 HCAR2 (0.42) HCAR2MAPTALDH1A1ATMKEAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2456764-B1 A METHOD OF MAKING A POLYMER PREFERABLY AN (ALKYL)ACRYLOYL POLYCARBONATE, THE POLYMER AND (ALKYL)ACRYLOYL POLYCARBONATE OBTAINED, AND A BIODEVICE COMPRISING SAME SSENS B V (NL) 2016-03-30 EP disclosed
US-8927196-B2 Method of making an (alkyl)acryloyl polycarbonate SSENS B.V. (NL) 2015-01-06 US disclosed
US-20120294845-A1 METHOD OF MAKING A POLYMER PREFERABLY AN (ALKYL) ACRYLOYL POLYCARBONATE, THE POLYMER AND (ALKYL) ACRYLOYL POLYCARBONATE OBTAINED, AND A BIODEVICE COMPRISING SAME SSENS B.V. (NL) 2012-11-22 US disclosed
EP-2456764-A1 A METHOD OF MAKING A POLYMER PREFERABLY AN (ALKYL)ACRYLOYL POLYCARBONATE, THE POLYMER AND (ALKYL)ACRYLOYL POLYCARBONATE OBTAINED, AND A BIODEVICE COMPRISING SAME Ssens B.V. (NL) 2012-05-30 EP disclosed
WO-2011009478-A1 A METHOD OF MAKING A POLYMER PREFERABLY AN (ALKYL)ACRYLOYL POLYCARBONATE, THE POLYMER AND (ALKYL)ACRYLOYL POLYCARBONATE OBTAINED, AND A BIODEVICE COMPRISING SAME SSENS B.V. (NL) 2011-01-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120294845-A1 METHOD OF MAKING A POLYMER PREFERABLY AN (ALKYL) ACRYLOYL POLYCARBONATE, THE POLYMER AND (ALKYL) ACRYLOYL POLYCARBONATE OBTAINED, AND A BIODEVICE COMPRISING SAME TET3, ALKBH3, ALKBH1 HCAR2 3199/4885FFAR3 597/4885MAPT 4718/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.