Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OTC | P00480 | 1/20 | 0.48 |
| ▸ | NOS2 | P35228 | 6/20 | 0.43 |
| ▸ | NOS1 | P29475 | 5/20 | 0.43 |
| ▸ | NOS3 | P29474 | 4/20 | 0.43 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GSR | P00390 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.38 |
| ▸ | ARG1 | P05089 | 3/20 | 0.38 |
| ▸ | ARG2 | P78540 | 3/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL787839 | 0.87 | OTC (0.50) | OTCNOS2NOS1NOS3DDAH1 | |
| SCHEMBL25216092 | 0.87 | OTC (0.50) | OTCNOS2NOS1NOS3DDAH1 | |
| SCHEMBL21089975 | 0.84 | OTC (0.50) | OTCNOS2NOS1NOS3DDAH1 | |
| SCHEMBL3508097 | 0.84 | OTC (0.50) | OTCNOS2NOS1NOS3DDAH1 | |
| SCHEMBL1004634 | 0.84 | OTC (0.50) | OTCNOS2NOS1NOS3DDAH1 | |
| SCHEMBL8730134 | 0.84 | NOD1 (0.52) | OTCNOS2NOS1NOS3DDAH1 | |
| SCHEMBL12028765 | 0.84 | OTC (0.50) | OTCNOS2NOS1NOS3DDAH1 | |
| Tilarginine SCHEMBL1321022 | 0.83 | OTC (0.49) | OTCNOS2NOS1NOS3DDAH1 | |
| SCHEMBL21111056 | 0.83 | DPP7 (0.58) | OTCNOS2NOS1NOS3DDAH1 | |
| SCHEMBL30544644 | 0.83 | OTC (0.49) | OTCNOS2NOS1NOS3DDAH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8202892-B2 | Advanced glycation end products as active ingredients | HENKEL AG & CO. KGAA (DE) | 2012-06-19 | — | — | US | disclosed |
| US-8202892-B2 | Advanced glycation end products as active ingredients | HENKEL AG & CO. KGAA (DE) | 2012-06-19 | — | — | US | disclosed |
| WO-2011131474-A2 | SKIN-GENTLE DEODORANTS AND ANTIPERSPIRANTS | HENKEL AG & CO. KGAA (DE) | 2011-10-27 | — | — | WO | disclosed |
| US-20100204176-A1 | ADVANCED GLYCATION END PRODUCTS AS ACTIVE INGREDIENTS | HENKEL AG & CO. KGAA (DE) | 2010-08-12 | — | — | US | disclosed |
| US-20100204176-A1 | ADVANCED GLYCATION END PRODUCTS AS ACTIVE INGREDIENTS | HENKEL AG & CO. KGAA (DE) | 2010-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100204176-A1 | ADVANCED GLYCATION END PRODUCTS AS ACTIVE INGREDIENTS | AGER, GLA, TYR | OTC 593/4885NOS2 163/4885NOS1 95/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.