Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 18/20 | 0.76 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.69 |
| ▸ | ERBB2 | P04626 | 8/20 | 0.61 |
| ▸ | RAF1 | P04049 | 1/20 | 0.59 |
| ▸ | BRAF | P15056 | 1/20 | 0.59 |
| ▸ | ERBB4 | Q15303 | 3/20 | 0.58 |
| ▸ | FYN | P06241 | 1/20 | 0.56 |
| ▸ | SRC | P12931 | 1/20 | 0.56 |
| ▸ | BLK | P51451 | 1/20 | 0.56 |
| ▸ | BMX | P51813 | 1/20 | 0.56 |
| ▸ | JAK3 | P52333 | 1/20 | 0.56 |
| ▸ | BTK | Q06187 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13889848 | 0.88 | EGFR (0.77) | EGFRERBB2FYN | |
| SCHEMBL2100347 | 0.87 | EGFR (0.77) | EGFRABCG2ERBB2 | |
| SCHEMBL27758510 | 0.87 | EGFR (0.76) | EGFRABCG2ERBB2RAF1BRAF | |
| SCHEMBL8871003 | 0.86 | EGFR (0.76) | EGFRABCG2ERBB2 | |
| SCHEMBL12012727 | 0.86 | EGFR (1.00) | EGFRABCG2ERBB2ERBB4FYN | |
| SCHEMBL13283264 | 0.85 | EGFR (0.61) | EGFRABCG2ERBB2RAF1BRAF | |
| SCHEMBL8870109 | 0.85 | EGFR (0.76) | EGFRABCG2ERBB2BRAF | |
| SCHEMBL7914891 | 0.85 | FYN (0.78) | EGFRERBB2ERBB4FYNSRC | |
| SCHEMBL24249504 | 0.84 | GMPS (0.77) | EGFRABCG2RAF1BRAFSRC | |
| SCHEMBL29392392 | 0.84 | GMPS (0.77) | EGFRABCG2RAF1BRAFSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120156228-A1 | Methods, Kits, and Compositions for Generating New Hair Follicles and Growing Hair | FOLLICA, INC. (US) | 2012-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120156228-A1 | Methods, Kits, and Compositions for Generating New Hair Follicles and Growing Hair | NGF, HDGF, SHH | EGFR 85/4885ABCG2 4728/4885ERBB2 830/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.