SCHEMBL9974897

SCHEMBL9974897

Bc1ccc(-c2ccccc2)nc1

nearest known ligand 0.52

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LDHA P00338 1/20 0.52
CYP11B1 P15538 9/20 0.46
CYP11B2 P19099 9/20 0.46
HPGDS O60760 2/20 0.46
BAZ2B Q9UIF8 1/20 0.44
MEN1 O00255 2/20 0.41
RAB9A P51151 2/20 0.41
KMT2A Q03164 2/20 0.41
CYP3A4 P08684 1/20 0.40
NPC1 O15118 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21202766 0.96 LDHA (0.48) LDHACYP11B1CYP11B2HPGDSBAZ2B
SCHEMBL23018675 0.88 NPC1 (0.38) LDHACYP11B1CYP11B2HPGDSRAB9A
SCHEMBL20068615 0.80 CCR1 (0.46) RAB9ANPC1SMN1; SMN2
SCHEMBL21202937 0.79 MEN1 (0.47) LDHACYP11B1CYP11B2HPGDSBAZ2B
SCHEMBL23018824 0.78 KDM1A (0.49) MEN1RAB9AKMT2ANPC1SMN1; SMN2
SCHEMBL12973036 0.78 HPGDS (0.60) LDHACYP11B1CYP11B2HPGDSBAZ2B
SCHEMBL21203023 0.78 MEN1 (0.50) LDHAHPGDSMEN1KMT2ASMN1; SMN2
SCHEMBL19933642 0.77 LDHA (0.47) LDHACYP11B1CYP11B2HPGDSBAZ2B
SCHEMBL25118611 0.76 HPGDS (0.58) LDHACYP11B1CYP11B2HPGDSBAZ2B
SCHEMBL12523550 0.76 HPGDS (0.58) LDHACYP11B1CYP11B2HPGDSBAZ2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018041769-A1 BINUCLEAR AND TRINUCLEAR METAL COMPLEXES COMPOSED OF TWO INTER-LINKED TRIPODAL HEXADENTATE LIGANDS FOR USE IN ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2018-03-08 WO disclosed
WO-2012081541-A1 1, 2, 4, 5-SUBSTITUTED PHENYL DERIVATIVE, PRODUCTION METHOD FOR SAME, AND ORGANIC ELECTROLUMINESCENT ELEMENT 東ソー株式会社 (JP) 2012-06-21 WO disclosed
EP-2298828-A1 POLYMERIC COMPOUND CONTAINING METAL COMPLEX RESIDUE AND ELEMENT COMPRISING SAME Sumitomo Chemical Company, Limited (JP) 2011-03-23 EP disclosed