Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL997440 | 0.82 | ALDH1A1 (0.42) | TSHRCTDSP1LMNAMEN1KMT2A | |
| SCHEMBL9815790 | 0.81 | TSHR (0.39) | TSHRHTTCTDSP1LMNAMEN1 | |
| SCHEMBL25306059 | 0.80 | ALDH1A1 (0.49) | TSHRCTDSP1LMNAMEN1KMT2A | |
| SCHEMBL9224528 | 0.80 | TSHR (0.50) | TSHRHTTCTDSP1MEN1KMT2A | |
| SCHEMBL10965817 | 0.79 | MEN1 (0.42) | TSHRHTTLMNAMEN1KMT2A | |
| SCHEMBL9139083 | 0.78 | TSHR (0.58) | TSHRHTTCTDSP1LMNAALDH1A1 | |
| SCHEMBL28802321 | 0.78 | TSHR (0.52) | TSHRHTTCTDSP1LMNAKMT2A | |
| SCHEMBL27901771 | 0.78 | TSHR (0.49) | TSHRHTTLMNAKMT2ACYP3A4 | |
| SCHEMBL10710710 | 0.77 | TSHR (0.57) | TSHRHTTCTDSP1LMNAKMT2A | |
| SCHEMBL996210 | 0.76 | LMNA (0.51) | TSHRCTDSP1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8809574-B2 | Method for preparing isocyanates by liquid-phase thermal cracking | LANZHOU INSTITUTE OF CHEMICAL PHYSICS, CHINESE ACADEMY OF SCIENCES (CN) | 2014-08-19 | — | — | US | disclosed |
| US-20110021810-A1 | METHOD FOR PREPARING ISOCYANATES BY LIQUID-PHASE THERMAL CRACKING | LANZHOU INSTITUTE OF CHEMICAL PHYSICS, CHINESE ACADEMY OF SCIENCES (CN) | 2011-01-27 | — | — | US | disclosed |
| EP-0143320-B1 | METHOD FOR THE PREPARATION OF ISOCYANATES BY THERMAL DECOMPOSITION OF URETHANES | BASF Aktiengesellschaft (DE) | 1988-01-20 | — | — | EP | disclosed |
| US-4613466-A | ZINC OR ALLOY CATALYST FOR THERMAL CLEAVAGE OF URETHANES | BASF AKTIENGESELLSCHAFT (DE) | 1986-09-23 | — | — | US | disclosed |
| EP-0100047-B1 | PROCESS FOR THE PREPARATION OF HEXAMETHYLENE DIISOCYANATE-1,6 AND/OR OF THE ISOMERIC DIISOCYANATES WITH 6 CARBON ATOMS IN THE ALKYL GROUP | BASF Aktiengesellschaft (DE) | 1986-02-12 | — | — | EP | disclosed |
| EP-0078005-B1 | METHOD FOR THE PREPARATION OF ISOCYANATES BY PYROLYSIS OF URETHANES | BASF Aktiengesellschaft (DE) | 1985-08-07 | — | — | EP | disclosed |
| US-4530796-A | Vapor phase pyrolysis | BASF AKTIENGESELLSCHAFT (DE) | 1985-07-23 | — | — | US | disclosed |
| EP-0143320-A2 | Method for the preparation of isocyanates by thermal decomposition of urethanes | BASF Aktiengesellschaft (DE) | 1985-06-05 | — | — | EP | disclosed |
| US-4482499-A | IN THE PRESENCE OF CARBON | BASF AKTIENGESELLSCHAFT (DE) | 1984-11-13 | — | — | US | disclosed |
| EP-0100047-A1 | Process for the preparation of hexamethylene diisocyanate-1,6 and/or of the isomeric diisocyanates with 6 carbon atoms in the alkyl group | BASF Aktiengesellschaft (DE) | 1984-02-08 | — | — | EP | disclosed |
| EP-0078005-A1 | Method for the preparation of isocyanates by pyrolysis of urethanes | BASF Aktiengesellschaft (DE) | 1983-05-04 | — | — | EP | disclosed |
| US-4349484-A | Process for the manufacture of mixtures of diphenylmethane diisocyanates and polyphenyl polymethylene polyisocyanates | BASF AKTIENGESELLSCHAFT (DE) | 1982-09-14 | — | — | US | disclosed |
| US-4330479-A | ZINC OR ALUMINUM CATALYST | BASF AKTIENGESELLSCHAFT (DE) | 1982-05-18 | — | — | US | disclosed |
| US-4290970-A | Process for the manufacture of aromatic di- and/or polyisocyanates | BASF AKTIENGESELLSCHAFT (DE) | 1981-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110021810-A1 | METHOD FOR PREPARING ISOCYANATES BY LIQUID-PHASE THERMAL CRACKING | DBI, CCNI, DGKI | TSHR 4586/4885HTT 257/4885CTDSP1 1028/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.