Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31490121 | 1.00 | ALDH1A1 (0.49) | ALDH1A1GAAGFERALOX15ALOX12 | |
| SCHEMBL11888516 | 0.85 | ALOX15 (0.45) | ALOX15ALOX12CYP4F2CYP4A11SMN1; SMN2 | |
| SCHEMBL7153462 | 0.83 | ALOX15 (0.51) | ALDH1A1GAAALOX15ALOX12SMN1; SMN2 | |
| SCHEMBL12367132 | 0.82 | ALOX15 (0.50) | ALDH1A1GAAALOX15ALOX12SMN1; SMN2 | |
| SCHEMBL25494165 | 0.79 | ALOX15 (0.40) | ALDH1A1ALOX15ALOX12SMN1; SMN2NPC1 | |
| SCHEMBL13384485 | 0.77 | ALOX15 (0.56) | ALDH1A1ALOX15ALOX12SMN1; SMN2NPC1 | |
| SCHEMBL30523664 | 0.77 | HIF1A (0.46) | ALDH1A1GAAGFERCYP4F2CYP4A11 | |
| SCHEMBL20766930 | 0.77 | HIF1A (0.46) | ALDH1A1GAAGFERCYP4F2CYP4A11 | |
| SCHEMBL19926744 | 0.76 | SMN1; SMN2 (0.57) | ALDH1A1GAAGFERALOX15SMN1; SMN2 | |
| SCHEMBL1744784 | 0.76 | SMN1; SMN2 (0.64) | ALDH1A1SMN1; SMN2NPC1RAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023078464-A1 | EPSILON-POLY-L-LYSINE-BASED DRUG CONJUGATE, INTERMEDIATE THEREOF, AND APPLICATION THEREOF | 上海弼领生物技术有限公司 | 2023-05-11 | — | — | WO | disclosed |
| WO-2019171088-A1 | BIOISPIRED PROTEASOME ACTIVATORS WITH ANTIAGEING ACTIVITY | NATIONAL HELLENIC RESEARCH FOUNDATION (GR) | 2019-09-12 | — | — | WO | disclosed |
| EP-2666761-A1 | HYDROXYTYROSOL ETHERS | Fundacio Imim (ES) | 2013-11-27 | — | — | EP | disclosed |
| US-20130267588-A1 | HYDROXYTYROSOL ETHERS | FUNDACIO IMIM (ES) | 2013-10-10 | — | — | US | disclosed |
| US-20130267588-A1 | HYDROXYTYROSOL ETHERS | FUNDACIO IMIM (ES) | 2013-10-10 | — | — | US | disclosed |
| US-20130267588-A1 | HYDROXYTYROSOL ETHERS | FUNDACIO IMIM (ES) | 2013-10-10 | — | — | US | disclosed |
| WO-2012080555-A1 | HYDROXYTYROSOL ETHERS | FUNDACIÓ IMIM (ES) | 2012-06-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130267588-A1 | HYDROXYTYROSOL ETHERS | CNR1, CNR2, HCRTR1 | ALDH1A1 1182/4885GAA 3445/4885GFER 867/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.