SCHEMBL9975743

SCHEMBL9975743

COc1cc(CO)c(C(=O)Oc2ccc(C(C)=O)cc2)cc1OC

nearest known ligand 0.64

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 11/20 0.64
ALDH1A1 P00352 4/20 0.46
TDP1 Q9NUW8 1/20 0.46
POLB P06746 2/20 0.44
MEN1 O00255 2/20 0.44
GAA P10253 1/20 0.43
MAPT P10636 2/20 0.43
SMN1; SMN2 Q16637 1/20 0.42
KDM4E B2RXH2 1/20 0.42
HPGD P15428 1/20 0.42
PKM P14618 1/20 0.42
GLA P06280 1/20 0.42
TSHR P16473 1/20 0.42
SIRT5 Q9NXA8 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9977559 0.85 KMT2A (0.76) KMT2AALDH1A1TDP1POLBMEN1
SCHEMBL12536786 0.83 ALDH1A1 (0.46) KMT2AALDH1A1TDP1MEN1MAPT
SCHEMBL17431105 0.83 KMT2A (0.48) KMT2AALDH1A1TDP1POLBMEN1
SCHEMBL12536698 0.81 ALDH1A1 (0.48) KMT2AALDH1A1TDP1MEN1MAPT
SCHEMBL12536793 0.80 ALDH1A1 (0.43) KMT2AALDH1A1MEN1GAAMAPT
SCHEMBL13121209 0.80 KMT2A (0.52) KMT2AALDH1A1POLBMEN1MAPT
SCHEMBL13121216 0.78 KMT2A (0.54) KMT2AALDH1A1MEN1GAAMAPT
SCHEMBL12536633 0.78 KMT2A (0.53) KMT2AALDH1A1POLBMEN1MAPT
SCHEMBL12536643 0.77 KMT2A (0.55) KMT2AALDH1A1TDP1MEN1GAA
SCHEMBL12536811 0.76 ALDH1A1 (0.45) KMT2AALDH1A1MEN1MAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9223070-B2 Optical film, polarizing plate equipped with the optical film, process for manufacture of the polarizing plate, and liquid crystal display device Konica Minolta, Inc. (JP) 2015-12-29 US disclosed
US-20130293812-A1 OPTICAL FILM, POLARIZING PLATE EQUIPPED WITH THE OPTICAL FILM, PROCESS FOR MANUFACTURE OF THE POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE Konica Minolta, Inc. (JP) 2013-11-07 US disclosed
US-20120156399-A1 CELLULOSE ESTER FILM, POLARIZING PLATE, LIQUID CRYSTAL DISPLAY AND PROCESS FOR PRODUCING CELLULOSE ESTER FILM FUJIFILM CORPORATION (JP) 2012-06-21 US disclosed