Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26927350 | 0.95 | TSHR (0.39) | USP2HSD17B10TSHRTDP1ALDH1A1 | |
| SCHEMBL5013566 | 0.92 | THRB (0.35) | USP2HSD17B10TDP1ALDH1A1 | |
| SCHEMBL10766196 | 0.86 | ALDH1A1 (0.42) | USP2HSD17B10TSHRTDP1ALDH1A1 | |
| SCHEMBL11598782 | 0.83 | TSHR (0.50) | USP2HSD17B10TSHRALDH1A1CNR1 | |
| SCHEMBL4904318 | 0.81 | TSHR (0.39) | TSHRALDH1A1 | |
| SCHEMBL2499893 | 0.81 | ALDH1A1 (0.42) | TSHRALDH1A1 | |
| SCHEMBL9019108 | 0.81 | ALDH1A1 (0.42) | TSHRALDH1A1 | |
| Ethylene Glycol SCHEMBL28214676 | 0.81 | TSHR (0.48) | USP2HSD17B10TSHRALDH1A1CNR1 | |
| SCHEMBL29372863 | 0.79 | USP2 (0.50) | USP2HSD17B10TSHRALDH1A1CNR1 | |
| SCHEMBL16829859 | 0.79 | USP2 (0.50) | USP2HSD17B10TSHRALDH1A1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2264486-B1 | Ophthalmic, tinted molding composition, molding having high Dk-value and method of its production | NOVARTIS AG (CH) | 2018-08-22 | — | — | EP | disclosed |
| US-9612455-B2 | Extended wear ophthalmic lens | NOVARTIS AG (CH) | 2017-04-04 | — | — | US | disclosed |
| EP-1360527-B1 | A TINTED, HIGH DK OPHTHALMIC MOLDING AND A METHOD FOR MAKING SAME | NOVARTIS AG (CH) | 2016-12-07 | — | — | EP | disclosed |
| US-9345988-B2 | Devices and method for continuous distillative separation of a mixture containing one or more alkanolamine(s) | BASF SE (DE) | 2016-05-24 | — | — | US | disclosed |
| US-8674140-B2 | Devices and method for continuous distillative separation of a mixture containing one or more alkanolamine(s) | BASF SE (DE) | 2014-03-18 | — | — | US | disclosed |
| US-20140061020-A1 | DEVICES AND METHOD FOR CONTINUOUS DISTILLATIVE SEPARATION OF A MIXTURE CONTAINING ONE OR MORE ALKANOLAMINE(S) | BASF SE (DE) | 2014-03-06 | — | — | US | disclosed |
| US-20140022507-A1 | Extended Wear Ophthalmic Lens | CIBA VISION CORPORATION (US) | 2014-01-23 | — | — | US | disclosed |
| US-8568626-B2 | Extended wear ophthalmic lens | CIBA VISION CORPORATION (US) | 2013-10-29 | — | — | US | disclosed |
| US-8415404-B2 | Extended wear ophthalmic lens | CIBA VISION CORPORATION (US) | 2013-04-09 | — | — | US | disclosed |
| EP-2270550-B1 | Extended wear contact lens | NOVARTIS AG (CH) | 2012-08-22 | — | — | EP | disclosed |
| EP-0865615-A1 | METHODS OF MANUFACTURING CONTACT LENSES | Novartis AG (CH) | 1998-09-23 | — | — | EP | disclosed |
| US-5789461-A | BIOCOMPATIBLE LENS HAVING HIGH OXYGEN PERMEABILITY AND HIGH WATER PERMEABILITY | CIBA VISION CORPORATION (US) | 1998-08-04 | — | — | US | disclosed |
| US-5776999-A | BALANCE OF OXYGEN AND WATER PERMEABILITY | CIBA VISION CORPORATION (US) | 1998-07-07 | — | — | US | disclosed |
| US-5760100-A | OXYGEN AND ION OR WATER PERMEABILITY | CIBA VISION CORPORATION (US) | 1998-06-02 | — | — | US | disclosed |
| EP-0822217-A1 | HETEROTELECHELIC BLOCK COPOLYMERS AND PROCESS FOR PRODUCING THE SAME | Kataoka, Kazunori (JP) | 1998-02-04 | — | — | EP | disclosed |
| EP-0819258-A1 | EXTENDED WEAR OPHTHALMIC LENS | Novartis AG (CH) | 1998-01-21 | — | — | EP | disclosed |
| EP-0809564-A1 | METHOD OF DEBLOCKING, EXTRACTING AND CLEANING POLYMERIC ARTICLES WITH SUPERCRITICAL FLUID | Novartis AG (CH) | 1997-12-03 | — | — | EP | disclosed |
| WO-1997022019-A1 | METHODS OF MANUFACTURING CONTACT LENSES | NOVARTIS AG (CH) | 1997-06-19 | — | — | WO | disclosed |
| WO-1996031792-A1 | EXTENDED WEAR OPHTHALMIC LENS | NOVARTIS AG (CH) | 1996-10-10 | — | — | WO | disclosed |
| WO-1996026059-A1 | METHOD OF DEBLOCKING, EXTRACTING AND CLEANING POLYMERIC ARTICLES WITH SUPERCRITICAL FLUID | NOVARTIS AG (CH) | 1996-08-29 | — | — | WO | disclosed |