Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 17/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 7/20 | 0.37 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.37 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.37 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.37 |
| ▸ | TLR2 | O60603 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9975870 | 0.90 | MAPK14 (0.30) | MAPK14 | |
| SCHEMBL9975874 | 0.87 | TLR2 (0.34) | TLR2 | |
| SCHEMBL10366691 | 0.85 | NR1I2 (0.34) | TLR2 | |
| SCHEMBL9975918 | 0.83 | KDM4E (0.45) | — | |
| SCHEMBL9975873 | 0.81 | ALDH1A1 (0.42) | TLR2 | |
| SCHEMBL10382630 | 0.81 | RAF1 (0.41) | RAF1MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL9975834 | 0.75 | NR1I2 (0.41) | — | |
| SCHEMBL9975907 | 0.73 | PTPRF (0.35) | — | |
| SCHEMBL9975780 | 0.72 | RAF1 (0.39) | RAF1MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL10381889 | 0.71 | ADRA2C (0.32) | RAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012083105-A1 | INHIBITORS OF HEPATITIS C VIRUS POLYMERASE | COCRYSTAL DISCOVERY, INC. (US) | 2012-06-21 | — | — | WO | disclosed |