Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 15/20 | 0.70 |
| ▸ | NPC1 | O15118 | 4/20 | 0.67 |
| ▸ | RAB9A | P51151 | 4/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9976456 | 0.93 | F10 (0.72) | F10NPC1RAB9AKDM4EMAPT | |
| SCHEMBL5409547 | 0.90 | F10 (0.81) | F10NPC1RAB9AMAPTKMT2A | |
| SCHEMBL5401508 | 0.83 | F10 (0.81) | F10NPC1RAB9AMAPTKMT2A | |
| SCHEMBL9976455 | 0.83 | F10 (1.00) | F10NPC1RAB9A | |
| SCHEMBL12082773 | 0.82 | RAB9A (1.00) | F10NPC1RAB9AKDM4EMAPT | |
| SCHEMBL12333906 | 0.80 | NPC1 (0.80) | F10NPC1RAB9AKDM4EMAPT | |
| SCHEMBL5406397 | 0.76 | F10 (0.83) | F10 | |
| SCHEMBL14593815 | 0.76 | F10 (0.76) | F10 | |
| SCHEMBL5409814 | 0.74 | F10 (0.84) | F10 | |
| SCHEMBL5399426 | 0.74 | F10 (1.00) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE43481-E1 | Diazepan derivatives or salts thereof | ASTELLAS PHARMA INC. (JP) | 2012-06-19 | — | — | US | disclosed |