Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MPI | P34949 | 1/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.37 |
| ▸ | ACACA | Q13085 | 2/20 | 0.36 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9976750 | 0.89 | CYP11B1 (0.49) | CYP11B1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL29396258 | 0.89 | CYP11B1 (0.56) | CYP11B1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL346901 | 0.89 | CYP11B1 (0.56) | CYP11B1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL22101164 | 0.88 | CYP11B1 (0.51) | CYP11B1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL13458897 | 0.86 | CYP11B1 (0.53) | CYP11B1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL13049747 | 0.86 | CYP11B1 (0.53) | CYP11B1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL9976755 | 0.84 | KDM4E (0.44) | CYP11B1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL17875449 | 0.83 | CYP11B1 (0.50) | CYP11B1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL13458690 | 0.80 | CYP11B1 (0.53) | CYP11B1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL1543078 | 0.80 | CYP11B1 (0.50) | CYP11B1KMT2AKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8877354-B2 | Heterocyclic compound and organic light-emitting device using the same | CANON KABUSHIKI KAISHA (JP) | 2014-11-04 | — | — | US | disclosed |
| US-8877354-B2 | Heterocyclic compound and organic light-emitting device using the same | CANON KABUSHIKI KAISHA (JP) | 2014-11-04 | — | — | US | disclosed |
| US-20120153270-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING THE SAME | CANON KABUSHIKI KAISHA (JP) | 2012-06-21 | — | — | US | disclosed |
| US-20120153270-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING THE SAME | CANON KABUSHIKI KAISHA (JP) | 2012-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120153270-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING THE SAME | ORC3, CYP1A1, CRY1 | CYP11B1 51/4885KMT2A 1886/4885KDM4E 2985/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.