SCHEMBL346901

SCHEMBL346901

c1ccc(-c2cc(-c3cc4ccccc4c4ccccc34)nc3c2ccc2c(-c4ccccc4)cc(-c4cc5ccccc5c5ccccc45)nc23)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 1/20 0.56
ALDH1A1 P00352 4/20 0.47
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
KDM4E B2RXH2 3/20 0.47
HPGD P15428 3/20 0.47
MAPT P10636 2/20 0.47
MPI P34949 1/20 0.47
GPR84 Q9NQS5 3/20 0.40
HPRT1 P00492 1/20 0.39
ACACA Q13085 2/20 0.39
NISCH Q9Y2I1 1/20 0.38
HIF1A Q16665 2/20 0.38
HSD17B10 Q99714 2/20 0.38
TSHR P16473 1/20 0.38
MAPK1 P28482 1/20 0.38
CASP1 P29466 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
RECQL P46063 1/20 0.38
HSD17B1 P14061 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29396258 1.00 CYP11B1 (0.56) CYP11B1ALDH1A1MEN1KMT2AKDM4E
SCHEMBL13049747 0.97 CYP11B1 (0.53) CYP11B1ALDH1A1MEN1KMT2AKDM4E
SCHEMBL13458897 0.97 CYP11B1 (0.53) CYP11B1ALDH1A1MEN1KMT2AKDM4E
SCHEMBL22101164 0.92 CYP11B1 (0.51) CYP11B1ALDH1A1MEN1KMT2AKDM4E
SCHEMBL1543078 0.90 CYP11B1 (0.50) CYP11B1ALDH1A1MEN1KMT2AKDM4E
SCHEMBL9976745 0.89 CYP11B1 (0.51) CYP11B1ALDH1A1MEN1KMT2AKDM4E
SCHEMBL13458690 0.88 CYP11B1 (0.53) CYP11B1ALDH1A1MEN1KMT2AKDM4E
SCHEMBL18101983 0.87 HPRT1 (0.45) CYP11B1ALDH1A1MEN1KMT2AKDM4E
SCHEMBL16696480 0.86 CYP11B1 (0.47) CYP11B1ALDH1A1MEN1KMT2AKDM4E
SCHEMBL14581511 0.84 CYP11B1 (0.45) CYP11B1ALDH1A1MEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11362285-B2 Semiconducting material and naphthofurane matrix compound for it NOVALED GMBH (DE) 2022-06-14 US disclosed
US-10862052-B2 Electrically doped organic semiconducting material and organic light emitting device comprising it NOVALED GMBH (DE) 2020-12-08 US disclosed
US-10811608-B2 N-doped semiconducting material comprising two metal dopants NOVALED GMBH (DE) 2020-10-20 US disclosed
US-RE48156-E1 Electronic device comprising an organic semiconducting material NOVALED GMBH (DE) 2020-08-11 US disclosed
US-10396293-B2 Electronic or optoelectronic device comprising an anchored thin molecular layer, process for its preparation and compound used therein NOVALED GMBH (DE) 2019-08-27 US disclosed
EP-2786435-B1 Compounds NOVALED GMBH (DE) 2019-07-17 EP disclosed
EP-2860782-B1 Semiconducting material comprising a phosphine oxide matrix and metal salt NOVALED GMBH (DE) 2019-04-17 EP disclosed
US-20180351100-A1 N-Doped Semiconducting Material Comprising Two Metal Dopants NOVALED GMBH (DE) 2018-12-06 US disclosed
US-10069078-B2 Semiconducting material comprising aza-substituted phosphine oxide matrix and metal salt NOVALED GMBH (DE) 2018-09-04 US disclosed
US-20180182960-A1 Organic Light Emitting Device Comprising Polar Matrix and Metal Dopant NOVALED GMBH (DE) 2018-06-28 US disclosed
US-8637858-B2 Tandem white OLED NOVALED AG (DE) 2014-01-28 US disclosed
US-20130200341-A1 Electronic Device Comprising an Organic Semiconducting Material NOVALED AG (DE) 2013-08-08 US disclosed
US-20120283437-A1 Organic Electronic Device Comprising an Organic Semiconducting Material NOVALED AG (DE) 2012-11-08 US disclosed
US-20120235122-A1 Organic Memory Element TECHNISCHE UNIVERSITAET DRESDEN (DE) 2012-09-20 US disclosed
US-20120119191-A1 Chemical Compound for Organic Electronic Device and Organic Electronic Device NOVALED AG (DE) 2012-05-17 US disclosed
US-20120074392-A1 Tandem White OLED NOVALED AG (DE) 2012-03-29 US disclosed
US-20120012794-A1 Bridged Pyridoquinazoline or Phenanthroline Compounds and Organic Semiconducting Material Comprising That Compound NOVALED AG (DE) 2012-01-19 US disclosed
US-20110220200-A1 Organic Photoactive Device NOVALED AG (DE) 2011-09-15 US disclosed
US-20080246395-A1 ORGANIC ELECTROLUMINESCENT DEVICE YAMAGATA PROMOTIONAL ORGANIZATION FOR INDUSTRIAL TECHNOLOGY (JP) 2008-10-09 US disclosed
US-20080246395-A1 ORGANIC ELECTROLUMINESCENT DEVICE YAMAGATA PROMOTIONAL ORGANIZATION FOR INDUSTRIAL TECHNOLOGY (JP) 2008-10-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11362285-B2 Semiconducting material and naphthofurane matrix compound for it NES, NQO1, VIM CYP11B1 1435/4885ALDH1A1 1096/4885MEN1 1255/4885
US-20120119191-A1 Chemical Compound for Organic Electronic Device and Organic Electronic Device SLCO4C1, OR10J3, EPCAM CYP11B1 100/4885ALDH1A1 409/4885MEN1 2165/4885
US-20120283437-A1 Organic Electronic Device Comprising an Organic Semiconducting Material OR10J3, OR51E2, ICMT CYP11B1 1746/4885ALDH1A1 264/4885MEN1 1309/4885
US-10069078-B2 Semiconducting material comprising aza-substituted phosphine oxide matrix and metal salt AZI2, ITPA, TET3 CYP11B1 4207/4885ALDH1A1 3761/4885MEN1 282/4885
US-20120012794-A1 Bridged Pyridoquinazoline or Phenanthroline Compounds and Organic Semiconducting Material Comprising That Compound PNPO, SDHB, PAH CYP11B1 1440/4885ALDH1A1 1384/4885MEN1 243/4885
US-10396293-B2 Electronic or optoelectronic device comprising an anchored thin molecular layer, process for its preparation and compound used therein EPCAM, OR10J3, OR51E2 CYP11B1 1289/4885ALDH1A1 1046/4885MEN1 2507/4885
US-10862052-B2 Electrically doped organic semiconducting material and organic light emitting device comprising it C1S, C5, HCN2 CYP11B1 2279/4885ALDH1A1 919/4885MEN1 855/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.