Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.70 |
| ▸ | APEX1 | P27695 | 1/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.46 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.46 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2801844 | 0.91 | CYP1A2 (0.84) | HPGDCYP1A2CYP2C9HSD17B10APEX1 | |
| SCHEMBL69064 | 0.83 | CYP1A2 (1.00) | HPGDCYP1A2CYP2C9HSD17B10APEX1 | |
| SCHEMBL29380400 | 0.83 | CYP1A2 (1.00) | HPGDCYP1A2CYP2C9HSD17B10APEX1 | |
| SCHEMBL29902348 | 0.81 | CA12 (0.58) | HPGDCYP1A2CYP2C9HSD17B10AKR1C3 | |
| SCHEMBL246827 | 0.81 | CA12 (0.58) | HPGDCYP1A2CYP2C9HSD17B10AKR1C3 | |
| SCHEMBL27957709 | 0.77 | ALDH1A1 (0.59) | HPGDCYP1A2CYP2C9HSD17B10APEX1 | |
| SCHEMBL4957430 | 0.77 | HSD17B10 (0.65) | HPGDCYP1A2CYP2C9HSD17B10APEX1 | |
| SCHEMBL1162110 | 0.77 | HSD17B10 (0.66) | HPGDCYP1A2CYP2C9HSD17B10APEX1 | |
| SCHEMBL28447751 | 0.77 | CYP1A2 (0.85) | HPGDCYP1A2CYP2C9HSD17B10APEX1 | |
| SCHEMBL6948021 | 0.77 | ALDH1A1 (0.69) | HPGDCYP1A2CYP2C9HSD17B10APEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8202997-B2 | Compositions and methods for treating or preventing hypoxic or ischemic injury | IKARIA, INC. (US) | 2012-06-19 | — | — | US | disclosed |
| US-20100130555-A1 | COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING HYPOXIC OR ISCHEMIC INJURY | IKARIA, INC. (US) | 2010-05-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100130555-A1 | COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING HYPOXIC OR ISCHEMIC INJURY | HIF1AN, HIF1A, HYOU1 | HPGD 26/4885CYP1A2 2503/4885CYP2C9 2318/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.