Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.43 |
| ▸ | TUBB | P07437 | 2/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.43 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.43 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.43 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.43 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.43 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.43 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.43 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.43 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYSLTR1 | Q9Y271 | 6/20 | 0.37 |
| ▸ | CYSLTR2 | Q9NS75 | 5/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL997828 | 0.93 | CA9 (0.50) | CA9TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL997747 | 0.93 | TUBB4A (0.46) | CA9TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL997165 | 0.85 | TSHR (0.54) | CA9TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL997868 | 0.81 | CA9 (0.45) | CA9TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL997717 | 0.78 | TUBB4A (0.39) | CA9TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL996876 | 0.78 | TUBB4A (0.59) | CA9TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL997102 | 0.77 | TUBB4A (0.43) | CA9TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL997928 | 0.76 | TUBB4A (0.46) | CA9TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL996712 | 0.76 | CA9 (0.45) | CA9TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL1395662 | 0.75 | ALDH1A1 (0.51) | CA9CYP3A4TSHRCYSLTR1CYSLTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011009826-A2 | NOVEL CHALCONE DERIVATIVES WITH CYTOTOXIC ACTIVITY | ADAMED Sp.z o.o. (PL) | 2011-01-27 | — | — | WO | disclosed |