Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HIF1AN | Q9NWT6 | 7/20 | 0.48 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.47 |
| ▸ | TUBB | P07437 | 2/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.47 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.47 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.47 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.47 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.47 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.47 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.47 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.47 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.47 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.47 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL997739 | 1.00 | KDM4E (0.51) | KDM4EALDH1A1HPGDHIF1ANTUBB4A | |
| SCHEMBL997043 | 0.93 | TUBB4A (0.57) | KDM4EALDH1A1HPGDHIF1ANTUBB4A | |
| SCHEMBL997045 | 0.93 | TUBB4A (0.57) | KDM4EALDH1A1HPGDHIF1ANTUBB4A | |
| SCHEMBL996176 | 0.89 | TUBB4A (0.59) | KDM4EALDH1A1HIF1ANTUBB4ATUBB | |
| SCHEMBL996177 | 0.89 | TUBB4A (0.59) | KDM4EALDH1A1HIF1ANTUBB4ATUBB | |
| Hydrochloric Acid SCHEMBL997709 | 0.89 | TUBB4A (0.58) | KDM4EALDH1A1HIF1ANTUBB4ATUBB | |
| Hydrochloric Acid SCHEMBL997707 | 0.89 | TUBB4A (0.58) | KDM4EALDH1A1HIF1ANTUBB4ATUBB | |
| SCHEMBL998658 | 0.87 | HIF1AN (0.51) | KDM4EALDH1A1HIF1ANTUBB4ATUBB | |
| SCHEMBL998657 | 0.87 | HIF1AN (0.51) | KDM4EALDH1A1HIF1ANTUBB4ATUBB | |
| SCHEMBL996808 | 0.86 | KDM4E (0.56) | KDM4EALDH1A1HPGDHIF1ANKEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011009826-A2 | NOVEL CHALCONE DERIVATIVES WITH CYTOTOXIC ACTIVITY | ADAMED Sp.z o.o. (PL) | 2011-01-27 | — | — | WO | claimed |
| WO-2011009826-A2 | NOVEL CHALCONE DERIVATIVES WITH CYTOTOXIC ACTIVITY | ADAMED Sp.z o.o. (PL) | 2011-01-27 | — | — | WO | disclosed |