Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM33 | Q9BZ11 | 5/20 | 0.59 |
| ▸ | MMP3 | P08254 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL997766 | 1.00 | ADAM33 (0.59) | ADAM33MMP3ALDH1A1TP53HSD17B10 | |
| SCHEMBL996087 | 0.87 | ADAM33 (0.57) | ADAM33MMP3ALDH1A1TP53 | |
| SCHEMBL996086 | 0.87 | ADAM33 (0.57) | ADAM33MMP3ALDH1A1TP53 | |
| SCHEMBL2680361 | 0.87 | ADAM33 (0.56) | ADAM33MMP3ALDH1A1TP53MAPT | |
| SCHEMBL2680366 | 0.87 | ADAM33 (0.56) | ADAM33MMP3ALDH1A1TP53MAPT | |
| SCHEMBL996483 | 0.84 | ADAM33 (0.84) | ADAM33MMP3ALDH1A1MAPT | |
| SCHEMBL996481 | 0.84 | ADAM33 (0.84) | ADAM33MMP3ALDH1A1MAPT | |
| SCHEMBL995406 | 0.83 | ADAM17 (0.55) | ADAM33MMP3 | |
| SCHEMBL997188 | 0.83 | ADAM17 (0.55) | ADAM33MMP3 | |
| SCHEMBL995407 | 0.83 | ADAM17 (0.55) | ADAM33MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2448931-B1 | Benzenesulfonamide compounds, method for synthesizing same, and use thereof in medicine | GALDERMA RES & DEV (FR) | 2015-05-27 | — | — | EP | disclosed |
| EP-2448931-A1 | NOVEL BENZENESULFONAMIDE COMPOUNDS, METHOD FOR SYNTHESIZING SAME, AND USE THEREOF IN MEDICINE AS WELL AS IN COSMETICS | Galderma Research & Development (FR) | 2012-05-09 | — | — | EP | disclosed |
| WO-2011001088-A1 | NOVEL BENZENESULFONAMIDE COMPOUNDS, METHOD FOR SYNTHESIZING SAME, AND USE THEREOF IN MEDICINE AS WELL AS IN COSMETICS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2011-01-06 | — | — | WO | disclosed |