Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13455172 | 0.88 | — | — | |
| SCHEMBL3175803 | 0.88 | — | — | |
| SCHEMBL21896589 | 0.84 | — | — | |
| SCHEMBL18799289 | 0.84 | — | — | |
| SCHEMBL17664772 | 0.84 | ODC1 (0.33) | — | |
| SCHEMBL13455122 | 0.81 | MAPK1 (0.32) | — | |
| SCHEMBL12261907 | 0.81 | — | — | |
| SCHEMBL18679428 | 0.81 | — | — | |
| SCHEMBL12446095 | 0.80 | ALDH1A1 (0.33) | ALDH1A1TSHR | |
| SCHEMBL25458359 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11833208-B2 | PLK1 selective degradation inducing compound | UPPTHERA, INC. (KR) | 2023-12-05 | — | — | US | disclosed |
| US-20230372498-A1 | PLK1 SELECTIVE DEGRADATION INDUCING COMPOUND | UPPTHERA (KR) | 2023-11-23 | — | — | US | disclosed |
| US-8263377-B2 | Label free kinase assays and reagents | PLEXERA, LLC (US) | 2012-09-11 | — | — | US | disclosed |
| US-20120157328-A1 | Label Free Kinase Assays and Reagents | SUZHOU PUXIN LIFE SCIENCE & TECHNOLOGY., LTD. (CN) | 2012-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230372498-A1 | PLK1 SELECTIVE DEGRADATION INDUCING COMPOUND | PLK1, BUB1B, BUB1 | ALDH1A1 3592/4885TSHR 4252/4885 |
| US-11833208-B2 | PLK1 selective degradation inducing compound | PLK1, BUB1B, BUB1 | ALDH1A1 3592/4885TSHR 4252/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.