Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | CYP4F2 | P78329 | 16/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 16/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL15327040 | 0.98 | LTA4H (0.48) | LTA4HNPSR1CYP4F2CYP4A11KDM4E | |
| SCHEMBL22968353 | 0.79 | CYP4F2 (0.75) | CYP4F2CYP4A11 | |
| SCHEMBL29595709 | 0.77 | NPSR1 (0.53) | NPSR1KDM4E | |
| SCHEMBL811160 | 0.77 | NPSR1 (0.53) | NPSR1KDM4E | |
| SCHEMBL9977744 | 0.77 | CYP4F2 (0.61) | LTA4HCYP4F2CYP4A11 | |
| SCHEMBL15338851 | 0.76 | JMJD6 (0.47) | CYP4F2CYP4A11 | |
| SCHEMBL22968112 | 0.75 | CYP4F2 (0.66) | CYP4F2CYP4A11 | |
| Hydrochloric Acid SCHEMBL15327060 | 0.75 | CYP4F2 (0.60) | LTA4HCYP4F2CYP4A11 | |
| Hydrochloric Acid SCHEMBL15327011 | 0.75 | JMJD6 (0.46) | CYP4F2CYP4A11 | |
| SCHEMBL5569809 | 0.74 | PDPK1 (0.61) | LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130281465-A1 | PYRAZOLE DERIVATIVE | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2013-10-24 | — | — | US | disclosed |
| US-20130281465-A1 | PYRAZOLE DERIVATIVE | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2013-10-24 | — | — | US | disclosed |
| WO-2012081692-A1 | PYRAZOLE DERIVATIVE | 大正製薬株式会社 (JP) | 2012-06-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130281465-A1 | PYRAZOLE DERIVATIVE | HCRTR1, HCRTR2, NPY4R | LTA4H 3100/4885NPSR1 35/4885CYP4F2 2278/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.