Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 11/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | QPCT | Q16769 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9978036 | 0.89 | MTNR1A (0.47) | CNR1CNR2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9978217 | 0.86 | CNR1 (0.50) | CNR1CNR2GAAPPARDPOLB | |
| SCHEMBL9978038 | 0.85 | MTNR1A (0.49) | CNR1CNR2PPARDPOLB | |
| SCHEMBL9978177 | 0.85 | PPARD (0.52) | CNR1CNR2HTTSMN1; SMN2PPARD | |
| SCHEMBL9937741 | 0.85 | CNR1 (0.50) | CNR1CNR2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9978222 | 0.84 | CNR2 (0.50) | CNR1CNR2PPARDPOLB | |
| SCHEMBL9978214 | 0.84 | CNR2 (0.48) | CNR1CNR2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9978063 | 0.83 | CNR2 (0.48) | CNR1CNR2PPARDKMT2AALDH1A1 | |
| SCHEMBL9978215 | 0.79 | CNR1 (0.48) | CNR1CNR2PPARDPOLB | |
| SCHEMBL9978045 | 0.79 | CNR1 (0.48) | CNR1CNR2PPARDKMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012079164-A1 | ACTIVATORS OF CYLINDRICAL PROTEASES | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2012-06-21 | — | — | WO | disclosed |