Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 7/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9978177 | 0.88 | PPARD (0.52) | CNR2CNR1KMT2APPARD | |
| SCHEMBL9937741 | 0.88 | CNR1 (0.50) | CNR2CNR1ALDH1A1PPARD | |
| SCHEMBL9978036 | 0.86 | MTNR1A (0.47) | CNR2CNR1ALDH1A1PPARD | |
| SCHEMBL9978217 | 0.83 | CNR1 (0.50) | CNR2CNR1KDM4EALDH1A1PPARD | |
| SCHEMBL9978222 | 0.83 | CNR2 (0.50) | CNR2CNR1PPARD | |
| SCHEMBL9978039 | 0.83 | CNR1 (0.48) | CNR2CNR1ALDH1A1KMT2APPARD | |
| SCHEMBL9978045 | 0.82 | CNR1 (0.48) | CNR2CNR1KDM4EALDH1A1KMT2A | |
| SCHEMBL9978214 | 0.81 | CNR2 (0.48) | CNR2CNR1MAPTPPARD | |
| SCHEMBL9978215 | 0.80 | CNR1 (0.48) | CNR2CNR1PPARD | |
| SCHEMBL9978006 | 0.79 | CNR1 (0.48) | CNR2CNR1PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012079164-A1 | ACTIVATORS OF CYLINDRICAL PROTEASES | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2012-06-21 | — | — | WO | disclosed |