Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADCY6 | O43306 | 1/20 | 0.37 |
| ▸ | ADCY3 | O60266 | 1/20 | 0.37 |
| ▸ | ADCY9 | O60503 | 1/20 | 0.37 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.37 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.37 |
| ▸ | GCGR | P47871 | 1/20 | 0.37 |
| ▸ | ADCY7 | P51828 | 1/20 | 0.37 |
| ▸ | ADCY2 | Q08462 | 1/20 | 0.37 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.37 |
| ▸ | ADCY4 | Q8NFM4 | 1/20 | 0.37 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 6/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2013699 | 0.83 | ABCC1 (0.34) | ABCC1KDM4EF10MCHR1ALDH1A1 | |
| SCHEMBL21173509 | 0.68 | TP53 (0.34) | ADCY6ADCY3ADCY9ADCY5ADCY8 | |
| SCHEMBL1331968 | 0.67 | — | — | |
| SCHEMBL1812485 | 0.60 | POLB (0.45) | MEN1KMT2A | |
| SCHEMBL23031606 | 0.59 | NR1I2 (0.54) | ALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL25653989 | 0.59 | NR1I2 (0.54) | ALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL26728740 | 0.58 | BDKRB2 (0.54) | KDM4EHPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL4438590 | 0.57 | KMT2A (0.52) | TP53ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6926258 | 0.57 | ABCC1 (0.76) | ABCC1ABCB1MCHR1ALDH1A1MEN1 | |
| SCHEMBL8755920 | 0.56 | PLK1 (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012082381-A1 | INDENO- FUSED RING COMPOUNDS HAVING PHOTOCHROMIC PROPERTIES | TRANSITIONS OPTICAL, INC. (US) | 2012-06-21 | — | — | WO | disclosed |