Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 15/20 | 0.51 |
| ▸ | CNR2 | P34972 | 6/20 | 0.49 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.40 |
| ▸ | KMO | O15229 | 1/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL411937 | 0.90 | CNR1 (0.52) | CNR1CNR2LRRK2KMO | |
| SCHEMBL9978027 | 0.81 | CNR1 (0.67) | CNR1CNR2 | |
| SCHEMBL9978233 | 0.80 | CNR1 (0.46) | CNR1CNR2 | |
| SCHEMBL2113754 | 0.76 | CNR1 (0.59) | CNR1CNR2 | |
| SCHEMBL9934999 | 0.76 | CNR2 (0.49) | CNR1CNR2 | |
| SCHEMBL442354 | 0.75 | CNR1 (0.67) | CNR1CNR2 | |
| SCHEMBL17142128 | 0.73 | CNR1 (0.47) | CNR1CNR2KMO | |
| SCHEMBL412180 | 0.73 | CNR1 (0.44) | CNR1CNR2 | |
| SCHEMBL30680327 | 0.72 | CNR2 (0.66) | CNR1CNR2KMOPTGER1 | |
| SCHEMBL411450 | 0.72 | CNR2 (0.66) | CNR1CNR2KMOPTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012080144-A1 | OXIME COMPOUNDS AS HDL-CHOLESTEROL RAISING AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 2012-06-21 | — | — | WO | disclosed |