Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.40 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.34 |
| ▸ | LCLAT1 | Q6UWP7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL410983 | 0.90 | CNR1 (0.48) | CNR1PTGS2PTGDR2KCNH2SCN5A | |
| SCHEMBL9978227 | 0.88 | SLC6A3 (0.41) | CNR1PTGS2SCN5AMAPTAPP | |
| SCHEMBL412280 | 0.88 | CNR1 (0.47) | CNR1PTGS2PTGDR2KCNH2SCN5A | |
| SCHEMBL9978231 | 0.81 | CNR1 (0.61) | CNR1PTGS2PTGDR2KCNH2SCN5A | |
| SCHEMBL9978011 | 0.81 | PTGDR2 (0.46) | CNR1PTGS2PTGDR2KCNH2SCN5A | |
| SCHEMBL411906 | 0.80 | CNR1 (0.44) | CNR1PTGS2PTGDR2KCNH2SCN5A | |
| SCHEMBL9978075 | 0.80 | CNR1 (0.51) | CNR1CNR2 | |
| SCHEMBL9931435 | 0.78 | KMO (0.47) | CNR1PTGS2MAPTNPSR1 | |
| SCHEMBL411097 | 0.77 | NPC1 (0.43) | CNR1KCNH2SCN5ASCN2ASCN10A | |
| SCHEMBL9973792 | 0.77 | CNR1 (0.74) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012080144-A1 | OXIME COMPOUNDS AS HDL-CHOLESTEROL RAISING AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 2012-06-21 | — | — | WO | disclosed |