Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9975317 | 0.83 | CHRM2 (0.40) | CHRM2CHRM1CHRM3 | |
| SCHEMBL15178495 | 0.78 | LMNA (0.32) | — | |
| SCHEMBL19371160 | 0.78 | LMNA (0.32) | — | |
| SCHEMBL15079602 | 0.78 | LMNA (0.32) | — | |
| SCHEMBL9092847 | 0.74 | CA1 (0.41) | CHRM2CHRM1CHRM3 | |
| SCHEMBL9978115 | 0.74 | CA1 (0.41) | CHRM2CHRM1CHRM3 | |
| SCHEMBL9978009 | 0.74 | CA1 (0.41) | CHRM2CHRM1CHRM3 | |
| SCHEMBL3751529 | 0.72 | CHRM2 (0.35) | CHRM2CHRM1CHRM3 | |
| SCHEMBL9931033 | 0.72 | CHRM2 (0.35) | CHRM2CHRM1CHRM3 | |
| SCHEMBL3654981 | 0.72 | CHRM2 (0.35) | CHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012080144-A1 | OXIME COMPOUNDS AS HDL-CHOLESTEROL RAISING AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 2012-06-21 | — | — | WO | disclosed |