Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 10/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.42 |
| ▸ | CTSA | P10619 | 2/20 | 0.41 |
| ▸ | TACR2 | P21452 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | LYN | P07948 | 1/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL410515 | 0.91 | CNR1 (0.48) | CNR1PTGS2S1PR1S1PR3S1PR5 | |
| SCHEMBL439869 | 0.91 | CNR1 (0.48) | CNR1PTGS2S1PR1S1PR3S1PR5 | |
| SCHEMBL412128 | 0.89 | CNR1 (0.49) | CNR1PTGS2S1PR1S1PR3S1PR5 | |
| SCHEMBL440364 | 0.89 | CNR1 (0.49) | CNR1PTGS2S1PR1S1PR3S1PR5 | |
| SCHEMBL412123 | 0.85 | PTGS2 (0.45) | CNR1PTGS2S1PR1S1PR3S1PR5 | |
| SCHEMBL460013 | 0.85 | PTGS2 (0.45) | CNR1PTGS2S1PR1S1PR3S1PR5 | |
| SCHEMBL9978231 | 0.81 | CNR1 (0.61) | CNR1PTGS2CTSATACR2 | |
| SCHEMBL2115645 | 0.81 | MAP4K4 (0.43) | CNR1PTGS2S1PR1S1PR3S1PR5 | |
| SCHEMBL410622 | 0.78 | CNR1 (0.45) | CNR1S1PR1S1PR3S1PR5CTSA | |
| SCHEMBL441620 | 0.78 | CNR1 (0.45) | CNR1S1PR1S1PR3S1PR5CTSA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012080144-A1 | OXIME COMPOUNDS AS HDL-CHOLESTEROL RAISING AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 2012-06-21 | — | — | WO | disclosed |