Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 12/20 | 0.61 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.45 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.45 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.45 |
| ▸ | TACR2 | P21452 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | CTSA | P10619 | 2/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL440662 | 0.89 | CNR1 (0.62) | CNR1PTGS2KCNH2SCN5ASCN2A | |
| SCHEMBL9978182 | 0.88 | CNR1 (0.49) | CNR1PTGS2KCNH2SCN5ASCN2A | |
| SCHEMBL2115870 | 0.82 | CNR1 (0.56) | CNR1PTGS2KCNH2SCN5ASCN2A | |
| SCHEMBL14783565 | 0.82 | CNR1 (0.55) | CNR1PTGS2KCNH2SCN5ASCN2A | |
| SCHEMBL14762057 | 0.82 | CNR1 (0.66) | CNR1KCNH2SCN5ASCN2ASCN10A | |
| SCHEMBL9978236 | 0.81 | CNR1 (0.48) | CNR1PTGS2TACR2CTSA | |
| SCHEMBL2114635 | 0.81 | CNR1 (0.52) | CNR1PTGS2KCNH2SCN5ASCN2A | |
| SCHEMBL9978233 | 0.81 | CNR1 (0.46) | CNR1PTGS2KCNH2SCN5ASCN2A | |
| SCHEMBL2714123 | 0.80 | SCN9A (0.43) | CNR1PTGS2SCN5AMAPTCNR2 | |
| SCHEMBL14762241 | 0.80 | CNR1 (0.58) | CNR1PTGS2KCNH2SCN5ASCN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012080144-A1 | OXIME COMPOUNDS AS HDL-CHOLESTEROL RAISING AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 2012-06-21 | — | — | WO | disclosed |