Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9978245 | 0.95 | RAB9A (0.58) | RAB9APOLBL3MBTL1HTTTSHR | |
| SCHEMBL4576862 | 0.88 | RAB9A (0.64) | RAB9APOLBL3MBTL1HTTTSHR | |
| SCHEMBL10120835 | 0.85 | RAB9A (0.61) | RAB9APOLBL3MBTL1HTTTSHR | |
| SCHEMBL1146693 | 0.84 | RAB9A (0.56) | RAB9APOLBL3MBTL1HTTTSHR | |
| SCHEMBL21702576 | 0.83 | L3MBTL1 (0.61) | RAB9APOLBL3MBTL1ALDH1A1GAA | |
| SCHEMBL14501994 | 0.83 | L3MBTL1 (0.61) | RAB9APOLBL3MBTL1ALDH1A1GAA | |
| SCHEMBL8416943 | 0.83 | L3MBTL1 (0.61) | RAB9APOLBL3MBTL1ALDH1A1GAA | |
| SCHEMBL4541731 | 0.83 | RAB9A (0.58) | RAB9APOLBHTTTSHRALDH1A1 | |
| SCHEMBL28064109 | 0.83 | RAB9A (0.58) | RAB9APOLBL3MBTL1HTTTSHR | |
| SCHEMBL3973116 | 0.81 | RAB9A (0.57) | RAB9AHTTTSHRALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010037760-A1 | COMPOUNDS WHICH POTENTIATE AMPA RECEPTOR AND USES THEREOF IN MEDICINE | GLAXO GROUP LIMITED (GB) | 2010-04-08 | — | — | WO | disclosed |