Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | CCR6 | P51684 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL176484 | 0.89 | TSHR (0.53) | TSHRALDH1A1HPGDLMNAALOX12 | |
| SCHEMBL9474547 | 0.87 | TSHR (0.49) | TSHRALDH1A1HPGDLMNAALOX12 | |
| SCHEMBL2226134 | 0.83 | HPGD (0.55) | TSHRALDH1A1HPGDSMN1; SMN2EGFR | |
| SCHEMBL9978415 | 0.83 | TSHR (0.52) | TSHRALDH1A1HPGDLMNAALOX12 | |
| SCHEMBL9474105 | 0.83 | TSHR (0.48) | TSHRALDH1A1HPGDLMNAALOX12 | |
| SCHEMBL11327615 | 0.83 | ALDH1A1 (0.62) | TSHRALDH1A1HPGDLMNAALOX12 | |
| SCHEMBL8089365 | 0.83 | HPGD (0.62) | TSHRALDH1A1HPGDOPRM1OPRD1 | |
| SCHEMBL4177603 | 0.79 | TSHR (0.46) | TSHRALDH1A1HPGDLMNAALOX12 | |
| SCHEMBL176438 | 0.79 | MEN1 (0.47) | TSHRALDH1A1HPGDLMNAALOX12 | |
| SCHEMBL11184042 | 0.78 | TSHR (0.53) | TSHRALDH1A1HPGDLMNAALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2576588-A1 | METHODS FOR THE SYNTHESIS OF ALKYNE-CONTAINING DICARBA BRIDGES IN PEPTIDES | Syngene Limited (AU) | 2013-04-10 | — | — | EP | disclosed |
| WO-2011146974-A1 | METHODS FOR THE SYNTHESIS OF ALKYNE-CONTAINING DICARBA BRIDGES IN PEPTIDES | MONASH UNIVERSITY (AU) | 2011-12-01 | — | — | WO | disclosed |