Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | IDO1 | P14902 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2366964 | 0.80 | CYP1A2 (0.48) | HTTIDO1MEN1KMT2ACYP3A4 | |
| SCHEMBL9978634 | 0.80 | CRHR1 (0.30) | — | |
| SCHEMBL9729609 | 0.70 | IDO1 (0.47) | HTTIDO1MEN1KMT2ACYP3A4 | |
| SCHEMBL2659771 | 0.69 | IDO1 (0.54) | HTTIDO1MEN1KMT2ACYP3A4 | |
| SCHEMBL2367025 | 0.69 | CYP3A4 (0.47) | HTTIDO1MEN1KMT2ACYP3A4 | |
| SCHEMBL8219998 | 0.68 | HTT (0.60) | HTTIDO1MEN1KMT2ACYP3A4 | |
| SCHEMBL13941323 | 0.68 | GAA (0.51) | HTTMEN1KMT2ACYP3A4CYP2C9 | |
| SCHEMBL2367386 | 0.68 | CYP3A4 (0.46) | HTTIDO1MEN1KMT2ACYP3A4 | |
| SCHEMBL10587518 | 0.67 | IDO1 (0.47) | HTTIDO1MEN1KMT2ACYP3A4 | |
| SCHEMBL3437067 | 0.67 | IDO1 (0.47) | HTTIDO1MEN1KMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2576515-B1 | Pyrazolecarboxamide derivatives and their use as microbiocides | SYNGENTA PARTICIPATIONS AG (CH) | 2014-04-16 | — | — | EP | disclosed |
| EP-2576515-B1 | Pyrazolecarboxamide derivatives and their use as microbiocides | SYNGENTA PARTICIPATIONS AG (CH) | 2014-04-16 | — | — | EP | disclosed |
| US-8552049-B2 | Pyrazolecarboxamide derivatives and their use as microbiocides | Syngenta Corp Protection, LLC (US) | 2013-10-08 | — | — | US | disclosed |
| US-8552049-B2 | Pyrazolecarboxamide derivatives and their use as microbiocides | Syngenta Corp Protection, LLC (US) | 2013-10-08 | — | — | US | disclosed |
| US-8552049-B2 | Pyrazolecarboxamide derivatives and their use as microbiocides | Syngenta Corp Protection, LLC (US) | 2013-10-08 | — | — | US | disclosed |
| EP-2576515-A1 | PYRAZOLECARBOXAMIDE DERIVATIVES AND THEIR USE AS MICROBIOCIDES | Syngenta Participations AG (CH) | 2013-04-10 | — | — | EP | disclosed |
| US-20130072535-A1 | PYRAZOLECARBOXAMIDE DERIVATIVES AND THEIR USE AS MICROBIOCIDES | SYNGENTA CROP PROTECTION LLC (US) | 2013-03-21 | — | — | US | disclosed |
| US-20130072535-A1 | PYRAZOLECARBOXAMIDE DERIVATIVES AND THEIR USE AS MICROBIOCIDES | SYNGENTA CROP PROTECTION LLC (US) | 2013-03-21 | — | — | US | disclosed |
| US-20130072535-A1 | PYRAZOLECARBOXAMIDE DERIVATIVES AND THEIR USE AS MICROBIOCIDES | SYNGENTA CROP PROTECTION LLC (US) | 2013-03-21 | — | — | US | disclosed |
| WO-2011147690-A1 | PYRAZOLECARBOXAMIDE DERIVATIVES AND THEIR USE AS MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2011-12-01 | — | — | WO | disclosed |
| WO-2011147690-A1 | PYRAZOLECARBOXAMIDE DERIVATIVES AND THEIR USE AS MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2011-12-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130072535-A1 | PYRAZOLECARBOXAMIDE DERIVATIVES AND THEIR USE AS MICROBIOCIDES | HRH4, MRGPRX4, C3AR1 | HTT 2391/4885IDO1 371/4885MEN1 1001/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.