SCHEMBL9979008

SCHEMBL9979008

Cc1cc(C)c(NC(=O)CC(CC(=O)Nc2c(C)cc(C)cc2C)C(=O)Nc2c(C)cc(C)cc2C)c(C)c1

nearest known ligand 0.57

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.57
HPGD P15428 2/20 0.51
POLB P06746 3/20 0.49
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49
TSHR P16473 1/20 0.49
ALDH1A1 P00352 2/20 0.49
ALOX15 P16050 1/20 0.48
MAPT P10636 1/20 0.47
TP53 P04637 1/20 0.47
NPSR1 Q6W5P4 2/20 0.46
GAA P10253 1/20 0.46
L3MBTL1 Q9Y468 2/20 0.45
HTT P42858 1/20 0.45
FUCA1 P04066 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9979097 0.86 LMNA (0.57) LMNAHPGDPOLBMEN1KMT2A
SCHEMBL2092062 0.77 LMNA (0.69) LMNAHPGDPOLBMEN1KMT2A
SCHEMBL9979140 0.77 HTT (0.69) LMNAMEN1KMT2AMAPTNPSR1
SCHEMBL2092059 0.76 LMNA (0.67) LMNAHPGDPOLBMEN1KMT2A
SCHEMBL14519900 0.76 ALDH1A1 (0.57) LMNAHPGDPOLBMEN1KMT2A
SCHEMBL12883186 0.76 TSHR (0.77) LMNAHPGDPOLBMEN1KMT2A
SCHEMBL9979141 0.76 KMT2A (0.68) LMNAHPGDMEN1KMT2AALDH1A1
SCHEMBL28253134 0.75 LMNA (0.47) LMNAHPGDPOLBMEN1KMT2A
SCHEMBL3899409 0.74 LMNA (0.96) LMNAHPGDPOLBMEN1KMT2A
SCHEMBL11578854 0.74 LMNA (0.70) LMNAHPGDPOLBMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8492468-B2 Polypropylene resin composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-07-23 US disclosed
US-20110301268-A1 POLYPROPYLENE RESIN COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-12-08 US disclosed