SCHEMBL9979183

SCHEMBL9979183

CCCc1ccccc1NC(=O)CC(CC(=O)Nc1ccccc1CCC)C(=O)Nc1ccccc1CCC

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.48
TAS1R3 Q7RTX0 1/20 0.47
TAS1R1 Q7RTX1 1/20 0.47
L3MBTL1 Q9Y468 2/20 0.46
POLB P06746 3/20 0.44
HDAC3 O15379 2/20 0.44
HDAC4 P56524 2/20 0.44
HDAC1 Q13547 2/20 0.44
HDAC7 Q8WUI4 2/20 0.44
HDAC2 Q92769 2/20 0.44
HDAC10 Q969S8 2/20 0.44
HDAC11 Q96DB2 2/20 0.44
HDAC8 Q9BY41 2/20 0.44
HDAC6 Q9UBN7 2/20 0.44
HDAC9 Q9UKV0 2/20 0.44
HDAC5 Q9UQL6 2/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
MAPK1 P28482 1/20 0.42
ALDH1A1 P00352 3/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9979216 0.92 POLB (0.49) TSHRTAS1R3TAS1R1L3MBTL1POLB
SCHEMBL9979375 0.90 TAS1R3 (0.48) TSHRTAS1R3TAS1R1L3MBTL1POLB
SCHEMBL9979215 0.89 HDAC3 (0.55) TSHRTAS1R3TAS1R1L3MBTL1POLB
SCHEMBL9979039 0.81 POLB (0.50) TSHRTAS1R3TAS1R1L3MBTL1POLB
SCHEMBL15706900 0.81 HDAC3 (0.51) TAS1R3TAS1R1POLBHDAC3HDAC4
SCHEMBL29580855 0.81 POLB (0.58) TAS1R3TAS1R1L3MBTL1POLBALDH1A1
SCHEMBL15093807 0.81 POLB (0.58) TAS1R3TAS1R1L3MBTL1POLBALDH1A1
SCHEMBL9979360 0.79 TSHR (0.44) TSHRTAS1R3TAS1R1L3MBTL1POLB
SCHEMBL18117420 0.78 MAPK1 (0.50) TAS1R3TAS1R1POLBHDAC3HDAC4
SCHEMBL28252416 0.78 ALDH1A1 (0.50) TAS1R3TAS1R1POLBHDAC3HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8492468-B2 Polypropylene resin composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-07-23 US disclosed
US-20110301268-A1 POLYPROPYLENE RESIN COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-12-08 US disclosed