SCHEMBL9979204

SCHEMBL9979204

CC(C)(C)c1ccccc1NC(=O)c1cc(C(=O)Nc2ccccc2C(C)(C)C)cc(C(=O)Nc2ccccc2C(C)(C)C)c1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TOP1 P11387 2/20 0.51
TOP2A P11388 1/20 0.51
TOP2B Q02880 1/20 0.51
ALDH1A1 P00352 2/20 0.51
RAB9A P51151 2/20 0.51
NPC1 O15118 1/20 0.51
GLA P06280 1/20 0.51
ATM Q13315 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
LPAR1 Q92633 1/20 0.50
MEN1 O00255 3/20 0.49
KMT2A Q03164 3/20 0.49
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
GRIN2D O15399 1/20 0.47
GRIN3B O60391 1/20 0.47
GRIN1 Q05586 1/20 0.47
GRIN2A Q12879 1/20 0.47
GRIN2B Q13224 1/20 0.47
GRIN2C Q14957 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10224266 0.89 POLB (0.61) ALDH1A1RAB9ANPC1GLAATM
SCHEMBL30625946 0.89 POLB (0.61) ALDH1A1RAB9ANPC1GLAATM
SCHEMBL2154596 0.85 NPC1 (0.62) ALDH1A1RAB9ANPC1GLAATM
SCHEMBL21652249 0.83 RAB9A (0.62) ALDH1A1RAB9ANPC1GLAATM
SCHEMBL21652294 0.83 MEN1 (0.70) ALDH1A1RAB9ANPC1GLAATM
SCHEMBL12666625 0.81 PTK2 (0.58) ALDH1A1RAB9ANPC1GLAATM
SCHEMBL12666628 0.81 NPC1 (0.57) ALDH1A1RAB9ANPC1GLAATM
SCHEMBL12666627 0.81 ALDH1A1 (0.44) ALDH1A1RAB9ANPC1GLAATM
SCHEMBL6448297 0.81 ALDH1A1 (0.55) ALDH1A1RAB9ANPC1L3MBTL1LPAR1
SCHEMBL12666624 0.80 ALDH1A1 (0.43) ALDH1A1RAB9ANPC1GLAATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8492468-B2 Polypropylene resin composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-07-23 US disclosed
US-20110301268-A1 POLYPROPYLENE RESIN COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-12-08 US disclosed