SCHEMBL9979327

SCHEMBL9979327

Cc1cc(F)ccc1NC(=O)CC(C(=O)Nc1ccc(F)cc1C)C(CC(=O)Nc1ccc(F)cc1C)C(=O)Nc1ccc(F)cc1C

nearest known ligand 0.54

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.54
MAPT P10636 4/20 0.54
KMT2A Q03164 3/20 0.47
MEN1 O00255 2/20 0.47
SLC1A3 P43003 1/20 0.47
SLC1A2 P43004 1/20 0.47
SLC1A1 P43005 1/20 0.47
LMNA P02545 4/20 0.46
THRB P10828 1/20 0.46
CHIT1 Q13231 1/20 0.45
HTT P42858 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
KDM4E B2RXH2 2/20 0.44
NPSR1 Q6W5P4 1/20 0.44
DRD4 P21917 1/20 0.43
TP53 P04637 1/20 0.43
POLB P06746 1/20 0.43
PKM P14618 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9978964 0.88 ALDH1A1 (0.54) ALDH1A1MAPTKMT2AMEN1SLC1A3
SCHEMBL9979067 0.85 KMT2A (0.68) ALDH1A1MAPTKMT2AMEN1LMNA
SCHEMBL9979041 0.81 MEN1 (0.46) ALDH1A1MAPTKMT2AMEN1SLC1A3
SCHEMBL9979179 0.81 MEN1 (0.46) ALDH1A1MAPTKMT2AMEN1SLC1A3
SCHEMBL17845244 0.80 LMNA (0.51) ALDH1A1MAPTKMT2AMEN1LMNA
SCHEMBL9979348 0.80 HPGD (0.60) ALDH1A1MAPTLMNASMN1; SMN2POLB
SCHEMBL9979256 0.79 MEN1 (0.44) ALDH1A1MAPTKMT2AMEN1SLC1A3
SCHEMBL9979383 0.79 MEN1 (0.44) ALDH1A1MAPTKMT2AMEN1SLC1A3
SCHEMBL4005420 0.78 ALDH1A1 (0.63) ALDH1A1MAPTKMT2AMEN1LMNA
SCHEMBL13541678 0.78 ALDH1A1 (0.59) ALDH1A1MAPTKMT2AMEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8492468-B2 Polypropylene resin composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-07-23 US disclosed
US-20110301268-A1 POLYPROPYLENE RESIN COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-12-08 US disclosed