SCHEMBL9979462

SCHEMBL9979462

Cc1ccc(Cc2ccc(-n3c(=O)c4cc5c(=O)n(C)c(=O)c5cc4c3=O)cc2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA9 Q16790 1/20 0.41
TP53 P04637 4/20 0.41
SMN1; SMN2 Q16637 3/20 0.41
KMT2A Q03164 3/20 0.39
LMNA P02545 3/20 0.39
ALDH1A1 P00352 3/20 0.39
KDM4E B2RXH2 2/20 0.39
HPGD P15428 2/20 0.39
GSK3A P49840 1/20 0.38
GSK3B P49841 1/20 0.38
MAPT P10636 2/20 0.38
MEN1 O00255 1/20 0.37
POLB P06746 1/20 0.37
NPC1 O15118 1/20 0.36
HSP90AA1 P07900 1/20 0.36
XBP1 P17861 1/20 0.36
MAPK1 P28482 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13411436 0.94 CA12 (0.46) CA12CA1CA2CA9SMN1; SMN2
SCHEMBL862493 0.90 CA12 (0.49) CA12CA1CA2CA9TP53
SCHEMBL13695372 0.88 CA12 (0.41) CA12CA1CA2CA9TP53
SCHEMBL760106 0.85 CA12 (0.45) CA12CA1CA2CA9TP53
SCHEMBL12780788 0.83 MEN1 (0.39) TP53SMN1; SMN2KMT2ALMNAALDH1A1
SCHEMBL13695390 0.83 SMN1; SMN2 (0.42) SMN1; SMN2KMT2ALMNAALDH1A1HPGD
SCHEMBL10014682 0.83 CA12 (0.55) CA12CA1CA2CA9TP53
SCHEMBL862788 0.82 CA12 (0.45) CA12CA1CA2CA9TP53
SCHEMBL758750 0.81 LMNA (0.44) CA12CA1CA2CA9TP53
SCHEMBL13618626 0.81 SMN1; SMN2 (0.40) TP53SMN1; SMN2KMT2ALMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230027931-A1 THERMOPLASTIC MOULDING COMPOSITION CONTAINING POLYALKYLENE TEREPHTHALATE BASF SE (DE) 2023-01-26 US disclosed
US-20200062995-A1 LOW GLOSS BLACK POLYIMIDE FILM COMPRISING A STRESS CANCELING RESIN LAYER AND A METHOD FOR PRODUCING THE SAME KUK DO CHEMICAL CO., LTD. (KR) 2020-02-27 US disclosed
US-20180090240-A1 ELECTRIC INSULATING MATERIAL, ELECTRIC INSULATING COATING COMPOUND AND ELECTRIC INSULATING WIRE HAVING EXCELLENT THERMAL CONDUCTION PERFORMANCE TOTOKU TORYO CO., LTD. (JP) 2018-03-29 US disclosed
US-9793483-B2 Hexafluoroisopropanol group-containing diamine, polyimide and polyamide using same, cyclized product thereof, and method for producing same CENTRAL GLASS COMPANY, LIMITED (JP) 2017-10-17 US disclosed
US-9701793-B2 Alignment film, method for preparing the same and liquid crystal display device comprising the same BOE TECHNOLOGY GROUP CO., LTD. (CN) 2017-07-11 US disclosed
US-20160152772-A1 Alignment Film, Method for Preparing the Same and Liquid Crystal Display Device Comprising the Same BEIJING BOE OPTOELECTRONICS TECHNOLOGY CO., LTD (CN) 2016-06-02 US disclosed
US-20140148571-A1 Hexafluoroisopropanol Group-Containing Diamine, Polyimide And Polyamide Using Same, Cyclized Product Thereof, And Method For Producing Same CENTRAL GLASS COMPANY, LIMITED (JP) 2014-05-29 US disclosed
US-20120120363-A1 LIQUID CRYSTAL DISPLAY ELEMENT SHARP KABUSHIKI KAISHA (JP) 2012-05-17 US disclosed
US-20090279925-A1 BELT FOR IMAGE FORMING APPARATUS NITTA CORPORATION (JP) 2009-11-12 US disclosed