SCHEMBL758750

SCHEMBL758750

Cc1ccc(Oc2ccc(-n3c(=O)c4cc5c(=O)n(C)c(=O)c5cc4c3=O)cc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.44
MAPT P10636 2/20 0.44
ALDH1A1 P00352 2/20 0.42
KMT2A Q03164 2/20 0.42
TP53 P04637 2/20 0.42
KDM4E B2RXH2 1/20 0.42
HPGD P15428 1/20 0.42
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA9 Q16790 1/20 0.41
NPSR1 Q6W5P4 2/20 0.41
RAB9A P51151 1/20 0.41
SMN1; SMN2 Q16637 3/20 0.40
MEN1 O00255 1/20 0.40
PDE10A Q9Y233 1/20 0.39
NPBWR1 P48145 1/20 0.39
KAT2B Q92831 1/20 0.39
GSK3A P49840 1/20 0.38
GSK3B P49841 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14513791 0.91 HTT (0.51) LMNAMAPTALDH1A1CA12CA1
SCHEMBL14701840 0.91 LMNA (0.38) LMNAMAPTALDH1A1KMT2ATP53
SCHEMBL12891169 0.91 KMT2A (0.44) LMNAMAPTALDH1A1KMT2ATP53
SCHEMBL862493 0.90 CA12 (0.49) LMNAMAPTALDH1A1KMT2ATP53
SCHEMBL14513787 0.88 HTT (0.43) LMNAMAPTALDH1A1KDM4ENPSR1
SCHEMBL12891173 0.88 MAPT (0.36) LMNAMAPTALDH1A1KMT2ATP53
SCHEMBL19797754 0.87 MEN1 (0.42) ALDH1A1KMT2AKDM4ECA12CA1
SCHEMBL47775 0.87 MEN1 (0.54) MAPTALDH1A1KMT2AHPGDCA12
SCHEMBL12900725 0.87 ALDH1A1 (0.48) LMNAMAPTALDH1A1TP53KDM4E
SCHEMBL13345921 0.87 MAPT (0.48) LMNAMAPTALDH1A1KMT2ATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 272 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3368285-B1 METHOD OF MAKING OPTICAL ARTICLES HAVING GRADIENT LIGHT INFLUENCING PROPERTIES TRANSITIONS OPTICAL INC (US) 2026-04-15 EP disclosed
EP-3368927-B1 OPTICAL ARTICLE WITH GRADIENT LIGHT INFLUENCING PROPERTIES AND METHOD OF MAKING THE SAME TRANSITIONS OPTICAL INC (US) 2024-10-16 EP disclosed
US-12076951-B2 Method of making optical articles having gradient light influencing properties TRANSITIONS OPTICAL, INC. (US) 2024-09-03 US disclosed
US-12055741-B2 Optical articles and method of preparing the same TRANSITIONS OPTICAL, INC. (US) 2024-08-06 US disclosed
US-20240218202-A1 ELECTRONIC TELECOMMUNICATIONS ARTICLES AND COMPOSITIONS COMPRISING FLUORINATED CURING AGENTS 3M INNOVATIVE PROPERTIES COMPANY 2024-07-04 US disclosed
US-20240209217-A1 FLUOROPOLYMER COMPOSITIONS COMPRISING UNCROSSLINKED FLUOROPOLYMER SUITABLE FOR COPPER AND ELECTRONIC TELECOMMUNICATIONS ARTICLES 3M INNOVATIVE PROPERTIES COMPANY 2024-06-27 US disclosed
US-12018127-B2 Additive manufacturing of aromatic thermoplastics from photocurable precursor salts VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) 2024-06-25 US disclosed
EP-3368926-B1 A METHOD OF MAKING AN OPTICAL ARTICLE WITH AN INKJET PRINTING DEVICE TRANSITIONS OPTICAL LTD (IE) 2024-03-06 EP disclosed
WO-2023238633-A1 RESIN DESIGNING SYSTEM, RESIN DESIGNING DEVICE, AND RESIN DESIGNING METHOD 株式会社日立製作所 2023-12-14 WO disclosed
US-20230386861-A1 SEMICONDUCTOR DEVICES AND METHODS OF MANUFACTURE TAIWAN SEMICONDUCTOR MFG CO LTD (TW) 2023-11-30 US disclosed
US-20070218335-A1 POLYMER HAVING OXOCARBON GROUP, AND USE THEREOF KAO CORPORATION (JP) 2007-09-20 US disclosed
US-7252881-B2 Multilayer structure and multilayer wiring board using the same KANEKA CORPORATION (JP) 2007-08-07 US disclosed
US-20070164466-A1 Method for producing filler-containing foam slabs BASF AKTIENGESELLSCHAFT (DE) 2007-07-19 US disclosed
US-20070128491-A1 Advanced solid acid electrolyte composites CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2007-06-07 US disclosed
US-7226664-B2 Laminated polyester film, flame-retardant polyester film thereof, copper-clad laminated plate and circuit substrate TORAY INDUSTRIES, INC. (JP) 2007-06-05 US disclosed
US-20070088125-A1 Polymers for use as alignment layers in liquid crystal devices ECSIBEO PPF2 AB (SE) 2007-04-19 US disclosed
US-20070066090-A1 Wiring board, process for producing the same polyimide film for use in the wiring board, and etchant for use in the process KANEKA CORPORATION (JP) 2007-03-22 US disclosed
US-20070059556-A1 Organic compound and organic light emitting device using the same LG CHEM. LTD. (KR) 2007-03-15 US disclosed
US-20070010628-A1 Cross-linked Sulphonated Polymers and Their Preparation Process MICHOT CHRISTOPHE 2007-01-11 US disclosed
US-20070001595-A1 Organic electroluminescence display and method of producing same CANON KABUSHIKI KAISHA (JP) 2007-01-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070059556-A1 Organic compound and organic light emitting device using the same SLCO4C1, TRPA1, OR51E2 LMNA 422/4885MAPT 1425/4885ALDH1A1 560/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.