Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.55 |
| ▸ | RAB9A | P51151 | 6/20 | 0.55 |
| ▸ | PKM | P14618 | 3/20 | 0.55 |
| ▸ | UGCG | Q16739 | 6/20 | 0.48 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.38 |
| ▸ | RELA | Q04206 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9979484 | 0.87 | UGCG (0.43) | NPC1RAB9APKMUGCGGRM1 | |
| SCHEMBL9979600 | 0.86 | UGCG (0.42) | NPC1RAB9APKMUGCGGRM1 | |
| SCHEMBL9979657 | 0.86 | NPC1 (0.55) | NPC1RAB9APKMUGCGGRM1 | |
| SCHEMBL9979554 | 0.83 | UGCG (0.43) | UGCGCBLB | |
| SCHEMBL9979662 | 0.81 | NPC1 (0.59) | NPC1RAB9APKMUGCGGRM1 | |
| SCHEMBL9979474 | 0.80 | UGCG (0.41) | NPC1RAB9APKMUGCGSMN1; SMN2 | |
| SCHEMBL9979465 | 0.78 | NPC1 (0.59) | NPC1RAB9APKMUGCGGRM1 | |
| SCHEMBL9979658 | 0.75 | UGCG (0.42) | NPC1RAB9APKMUGCGGRM1 | |
| SCHEMBL9979601 | 0.75 | NPC1 (0.55) | NPC1RAB9APKMUGCGGRM1 | |
| SCHEMBL9979580 | 0.73 | PKM (0.41) | NPC1RAB9APKMUGCGGRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012081570-A1 | LACTAM COMPOUND OR A SALT THEREOF, AND PPAR ACTIVATOR | あすか製薬株式会社 (JP) | 2012-06-21 | — | — | WO | disclosed |