Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | UGCG | Q16739 | 6/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | CASP3 | P42574 | 3/20 | 0.44 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PTPRC | P08575 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9979481 | 0.89 | SLC6A3 (0.49) | NPC1PKMRAB9AUGCGPOLB | |
| SCHEMBL9979630 | 0.89 | SLC6A4 (0.50) | NPC1PKMRAB9AUGCGPOLB | |
| SCHEMBL9979627 | 0.85 | UGCG (0.45) | NPC1PKMRAB9AUGCGPOLB | |
| SCHEMBL9979601 | 0.85 | NPC1 (0.55) | NPC1PKMRAB9AUGCGPOLB | |
| SCHEMBL9979466 | 0.84 | UGCG (0.44) | NPC1PKMRAB9AUGCGPOLB | |
| SCHEMBL9979465 | 0.78 | NPC1 (0.59) | NPC1PKMRAB9AUGCGGRM1 | |
| SCHEMBL9979662 | 0.75 | NPC1 (0.59) | NPC1PKMRAB9AUGCGGRM1 | |
| SCHEMBL21496764 | 0.75 | HDAC11 (0.47) | NPC1RAB9AKDM4EHSD17B10MAPT | |
| SCHEMBL9979657 | 0.75 | NPC1 (0.55) | NPC1PKMRAB9AUGCGCASP3 | |
| SCHEMBL9979473 | 0.72 | UGCG (0.45) | NPC1PKMRAB9AUGCGPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012081570-A1 | LACTAM COMPOUND OR A SALT THEREOF, AND PPAR ACTIVATOR | あすか製薬株式会社 (JP) | 2012-06-21 | — | — | WO | disclosed |