Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | PKM | P14618 | 2/20 | 0.55 |
| ▸ | UGCG | Q16739 | 5/20 | 0.48 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | CBLB | Q13191 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9979556 | 0.86 | GRM1 (0.43) | NPC1RAB9APKMUGCGGRM1 | |
| SCHEMBL9979599 | 0.86 | NPC1 (0.55) | NPC1RAB9APKMUGCGGRM1 | |
| SCHEMBL9979658 | 0.86 | UGCG (0.42) | NPC1RAB9APKMUGCGGRM1 | |
| SCHEMBL9979557 | 0.83 | UGCG (0.45) | UGCGCBLB | |
| SCHEMBL9979465 | 0.81 | NPC1 (0.59) | NPC1RAB9APKMUGCGGRM1 | |
| SCHEMBL9979552 | 0.80 | UGCG (0.41) | NPC1RAB9APKMUGCGCBLB | |
| SCHEMBL9979662 | 0.78 | NPC1 (0.59) | NPC1RAB9APKMUGCGGRM1 | |
| SCHEMBL9979601 | 0.78 | NPC1 (0.55) | NPC1RAB9APKMUGCGGRM1 | |
| SCHEMBL9979580 | 0.75 | PKM (0.41) | NPC1RAB9APKMUGCGGRM1 | |
| SCHEMBL9979478 | 0.75 | NPC1 (0.51) | NPC1RAB9APKMUGCGGRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012081570-A1 | LACTAM COMPOUND OR A SALT THEREOF, AND PPAR ACTIVATOR | あすか製薬株式会社 (JP) | 2012-06-21 | — | — | WO | disclosed |