Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 5/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9979667 | 0.93 | LMNA (0.43) | LMNAPOLBALDH1A1L3MBTL1NTRK1 | |
| SCHEMBL9979726 | 0.91 | LMNA (0.42) | LMNAPOLBALDH1A1L3MBTL1NTRK1 | |
| SCHEMBL13215993 | 0.89 | LMNA (0.41) | LMNAPOLBALDH1A1L3MBTL1NTRK1 | |
| SCHEMBL9979590 | 0.89 | LMNA (0.46) | LMNAPOLBALDH1A1L3MBTL1NTRK1 | |
| SCHEMBL9979603 | 0.87 | ATM (0.52) | LMNAPOLBALDH1A1L3MBTL1KDM4E | |
| SCHEMBL9979529 | 0.85 | LMNA (0.45) | LMNAPOLBALDH1A1L3MBTL1NTRK1 | |
| SCHEMBL14578046 | 0.83 | LMNA (0.68) | LMNAPOLBALDH1A1L3MBTL1NTRK1 | |
| SCHEMBL1085471 | 0.82 | LMNA (0.57) | LMNAPOLBALDH1A1L3MBTL1NTRK1 | |
| SCHEMBL14266795 | 0.82 | LMNA (0.54) | LMNAPOLBALDH1A1L3MBTL1NTRK1 | |
| SCHEMBL4100026 | 0.82 | NTRK1 (0.56) | LMNAPOLBALDH1A1NTRK1STING1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1305292-B1 | BIPHENYL CARBOXAMIDES | BAYER CROPSCIENCE AG (DE) | 2012-06-20 | — | — | EP | disclosed |
| US-20100216849-A1 | BIPHENYLCARBOXAMIDES | DUNKEL RALF | 2010-08-26 | — | — | US | disclosed |
| US-7728019-B2 | Biphenylcarboxamides | BAYER CROPSCIENCE AG (DE) | 2010-06-01 | — | — | US | disclosed |
| US-20080085924-A1 | Biphenylcaboxamides | BAYER CROPSCINCE AG (DE) | 2008-04-10 | — | — | US | disclosed |
| US-7176228-B2 | Pyrazole biphenylcarboxamides | BAYER CROPSCIENCE AG (DE) | 2007-02-13 | — | — | US | disclosed |
| US-7176228-B2 | Pyrazole biphenylcarboxamides | BAYER CROPSCIENCE AG (DE) | 2007-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080085924-A1 | Biphenylcaboxamides | AHR, Q6ZSR9, DDT | LMNA 1108/4885POLB 1531/4885ALDH1A1 415/4885 |
| US-20100216849-A1 | BIPHENYLCARBOXAMIDES | AHR, DDT, MRPL21 | LMNA 765/4885POLB 1106/4885ALDH1A1 478/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.