Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | DDX3X | O00571 | 1/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9979667 | 0.95 | LMNA (0.43) | LMNAPOLBSTING1NTRK1ALDH1A1 | |
| SCHEMBL9979537 | 0.91 | LMNA (0.47) | LMNAPOLBSTING1NTRK1ALDH1A1 | |
| SCHEMBL13215993 | 0.86 | LMNA (0.41) | LMNAPOLBSTING1NTRK1ALDH1A1 | |
| SCHEMBL14578270 | 0.86 | LMNA (0.43) | LMNAPOLBSTING1NTRK1PPARG | |
| SCHEMBL9979590 | 0.85 | LMNA (0.46) | LMNAPOLBSTING1NTRK1ALDH1A1 | |
| SCHEMBL14578336 | 0.83 | ATM (0.50) | LMNAPOLBALDH1A1KDM4ETSHR | |
| SCHEMBL14578115 | 0.81 | GAA (0.40) | LMNAPPARGPPARAALDH1A1KDM4E | |
| SCHEMBL9979541 | 0.80 | LMNA (0.44) | LMNAPOLBSTING1NTRK1PPARG | |
| SCHEMBL13936365 | 0.80 | GAA (0.57) | LMNAPOLBNTRK1ALDH1A1KDM4E | |
| SCHEMBL1085471 | 0.80 | LMNA (0.57) | LMNAPOLBNTRK1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1305292-B1 | BIPHENYL CARBOXAMIDES | BAYER CROPSCIENCE AG (DE) | 2012-06-20 | — | — | EP | disclosed |
| US-7176228-B2 | Pyrazole biphenylcarboxamides | BAYER CROPSCIENCE AG (DE) | 2007-02-13 | — | — | US | disclosed |
| US-7176228-B2 | Pyrazole biphenylcarboxamides | BAYER CROPSCIENCE AG (DE) | 2007-02-13 | — | — | US | disclosed |