Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 16/20 | 0.53 |
| ▸ | PPARA | Q07869 | 5/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | HTR1D | P28221 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4760401 | 0.94 | PPARD (0.46) | PPARDPPARADRD2HTR1DDRD3 | |
| SCHEMBL14061800 | 0.86 | CYP24A1 (0.48) | DRD2HTR1DDRD3 | |
| SCHEMBL3947555 | 0.86 | PPARD (0.65) | PPARDPPARAFFAR1 | |
| SCHEMBL821443 | 0.83 | PPARD (0.60) | PPARDPPARA | |
| SCHEMBL12035617 | 0.83 | PPARD (0.60) | PPARDPPARA | |
| SCHEMBL821099 | 0.83 | PPARD (0.60) | PPARDPPARA | |
| SCHEMBL8327308 | 0.82 | KMT2A (0.45) | PPARDDRD2HTR1DDRD3 | |
| SCHEMBL3962243 | 0.80 | PPARD (0.48) | PPARDPPARAFFAR1 | |
| SCHEMBL3969570 | 0.80 | PPARD (0.52) | PPARDPPARAFFAR1 | |
| SCHEMBL12798817 | 0.80 | PPARD (0.64) | PPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012081570-A1 | LACTAM COMPOUND OR A SALT THEREOF, AND PPAR ACTIVATOR | あすか製薬株式会社 (JP) | 2012-06-21 | — | — | WO | disclosed |