Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8147162 | 0.89 | LMNA (0.54) | LMNAMAPTGAAKDM4EGLA | |
| SCHEMBL15211675 | 0.84 | HSP90AB1 (0.49) | LMNAMAPTGAAKDM4EGLA | |
| SCHEMBL9366094 | 0.84 | MAPT (0.45) | LMNAMAPTGAAKDM4EGLA | |
| SCHEMBL5640191 | 0.84 | MTNR1A (0.57) | LMNAMAPTCYP1A2CYP2C19MEN1 | |
| SCHEMBL7492024 | 0.82 | FFAR1 (0.55) | LMNAMAPTKDM4ECYP1A2CYP3A4 | |
| SCHEMBL9365812 | 0.79 | ANPEP (0.59) | LMNAMAPTGAAKDM4EGLA | |
| SCHEMBL21102371 | 0.76 | APEX1 (0.42) | LMNAMAPTGAAKDM4EGLA | |
| SCHEMBL17045899 | 0.75 | HDAC1 (0.47) | LMNAMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL4551576 | 0.75 | APEX1 (0.66) | LMNAMAPTGAAKDM4ECYP1A2 | |
| SCHEMBL9361264 | 0.75 | MAPT (0.53) | LMNAMAPTGAAKDM4EGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012081570-A1 | LACTAM COMPOUND OR A SALT THEREOF, AND PPAR ACTIVATOR | あすか製薬株式会社 (JP) | 2012-06-21 | — | — | WO | disclosed |