Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 6/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.51 |
| ▸ | PPARA | Q07869 | 5/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9979669 | 0.92 | PPARD (0.53) | PPARDFFAR1PPARAPPARGMAPT | |
| SCHEMBL9979584 | 0.91 | POLB (0.44) | PPARDFFAR1MAPTHTTMEN1 | |
| SCHEMBL9979633 | 0.90 | PPARD (0.55) | PPARDFFAR1PPARAPPARGMAPT | |
| SCHEMBL9979623 | 0.90 | PPARD (0.67) | PPARDFFAR1PPARAPPARGPTGER4 | |
| SCHEMBL9979520 | 0.85 | PPARD (0.43) | PPARDFFAR1PPARAPPARGMAPT | |
| SCHEMBL9979500 | 0.83 | PPARD (0.51) | PPARDFFAR1PPARAPPARGPTGER4 | |
| SCHEMBL9979618 | 0.83 | PPARD (0.44) | PPARDFFAR1PPARAPPARGMAPT | |
| SCHEMBL9979510 | 0.83 | PPARD (0.53) | PPARDFFAR1PPARAPPARGMAPT | |
| SCHEMBL9979625 | 0.81 | MAPT (0.47) | FFAR1MAPTALOX15SMN1; SMN2HTT | |
| SCHEMBL9979526 | 0.76 | FFAR1 (0.58) | PPARDFFAR1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012081570-A1 | LACTAM COMPOUND OR A SALT THEREOF, AND PPAR ACTIVATOR | あすか製薬株式会社 (JP) | 2012-06-21 | — | — | WO | disclosed |