Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
| ▸ | PPARA | Q07869 | 3/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 2/20 | 0.35 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14578213 | 0.95 | HTT (0.40) | GAAKDM4EHTTSMN1; SMN2TDP1 | |
| SCHEMBL9979612 | 0.91 | HTT (0.41) | GAAKDM4EHTTSMN1; SMN2TDP1 | |
| SCHEMBL13215927 | 0.87 | HTT (0.40) | GAAKDM4EHTTSMN1; SMN2TDP1 | |
| SCHEMBL5341760 | 0.87 | HTT (0.43) | GAAKDM4EHTTSMN1; SMN2TDP1 | |
| SCHEMBL9979544 | 0.87 | HTT (0.43) | GAAKDM4EHTTSMN1; SMN2TDP1 | |
| SCHEMBL13215908 | 0.86 | KDM4E (0.39) | GAAKDM4EHTTSMN1; SMN2TDP1 | |
| SCHEMBL14578115 | 0.86 | GAA (0.40) | GAAKDM4EHTTSMN1; SMN2TDP1 | |
| SCHEMBL14578384 | 0.86 | KMT2A (0.43) | GAAKDM4EHTTSMN1; SMN2TDP1 | |
| SCHEMBL9979577 | 0.84 | HTT (0.41) | GAAKDM4EHTTSMN1; SMN2TDP1 | |
| SCHEMBL14578299 | 0.84 | HTT (0.45) | GAAKDM4EHTTSMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1305292-B1 | BIPHENYL CARBOXAMIDES | BAYER CROPSCIENCE AG (DE) | 2012-06-20 | — | — | EP | disclosed |
| US-7176228-B2 | Pyrazole biphenylcarboxamides | BAYER CROPSCIENCE AG (DE) | 2007-02-13 | — | — | US | disclosed |
| US-7176228-B2 | Pyrazole biphenylcarboxamides | BAYER CROPSCIENCE AG (DE) | 2007-02-13 | — | — | US | disclosed |