Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 13/20 | 0.40 |
| ▸ | PPARD | Q03181 | 12/20 | 0.40 |
| ▸ | PPARA | Q07869 | 12/20 | 0.40 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.36 |
| ▸ | UGCG | Q16739 | 2/20 | 0.35 |
| ▸ | HRH2 | P25021 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9979508 | 0.98 | PPARD (0.38) | PPARGPPARDPPARANR5A1UGCG | |
| SCHEMBL9979468 | 0.91 | PPARD (0.45) | PPARGPPARDPPARAUGCG | |
| SCHEMBL9979701 | 0.90 | PPARG (0.49) | PPARGPPARDPPARA | |
| SCHEMBL9979611 | 0.88 | PPARD (0.46) | PPARGPPARDPPARA | |
| SCHEMBL9979472 | 0.85 | GCGR (0.34) | PPARGPPARDPPARANR5A1UGCG | |
| SCHEMBL9979687 | 0.83 | PPARD (0.56) | PPARGPPARDPPARA | |
| SCHEMBL9979610 | 0.81 | PPARD (0.54) | PPARGPPARDPPARAUGCG | |
| SCHEMBL9979504 | 0.80 | PPARD (0.56) | PPARGPPARDPPARAUGCG | |
| SCHEMBL9979487 | 0.79 | PPARD (0.53) | PPARGPPARDPPARA | |
| SCHEMBL9979476 | 0.77 | PPARD (0.50) | PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012081570-A1 | LACTAM COMPOUND OR A SALT THEREOF, AND PPAR ACTIVATOR | あすか製薬株式会社 (JP) | 2012-06-21 | — | — | WO | disclosed |