Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 11/20 | 0.45 |
| ▸ | PPARA | Q07869 | 9/20 | 0.45 |
| ▸ | UGCG | Q16739 | 6/20 | 0.40 |
| ▸ | PPARG | P37231 | 8/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | HTR1B | P28222 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9979508 | 0.93 | PPARD (0.38) | PPARDPPARAUGCGPPARG | |
| SCHEMBL9979654 | 0.91 | PPARG (0.40) | PPARDPPARAUGCGPPARG | |
| SCHEMBL9979504 | 0.90 | PPARD (0.56) | PPARDPPARAUGCGPPARG | |
| SCHEMBL9979610 | 0.89 | PPARD (0.54) | PPARDPPARAUGCGPPARG | |
| SCHEMBL9979687 | 0.88 | PPARD (0.56) | PPARDPPARAPPARG | |
| SCHEMBL9979611 | 0.82 | PPARD (0.46) | PPARDPPARAPPARG | |
| SCHEMBL9979701 | 0.80 | PPARG (0.49) | PPARDPPARAPPARG | |
| SCHEMBL9979593 | 0.79 | PPARD (0.50) | PPARDPPARAUGCGPPARG | |
| SCHEMBL9979479 | 0.79 | PPARD (0.68) | PPARDPPARAUGCGPPARG | |
| SCHEMBL9979472 | 0.78 | GCGR (0.34) | PPARDPPARAUGCGPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012081570-A1 | LACTAM COMPOUND OR A SALT THEREOF, AND PPAR ACTIVATOR | あすか製薬株式会社 (JP) | 2012-06-21 | — | — | WO | disclosed |