Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 1/20 | 0.34 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 4/20 | 0.33 |
| ▸ | PPARA | Q07869 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | UGCG | Q16739 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9979531 | 0.91 | PPARD (0.42) | GCGRPPARDPPARAPPARGTRPV1 | |
| SCHEMBL9979508 | 0.85 | PPARD (0.38) | NR5A1PPARDPPARAMAPTPPARG | |
| SCHEMBL9979654 | 0.85 | PPARG (0.40) | NR5A1PPARDPPARAPPARGUGCG | |
| SCHEMBL9979703 | 0.79 | L3MBTL1 (0.36) | PPARDPPARAPOLBALDH1A1MAPT | |
| SCHEMBL9979609 | 0.79 | PPARA (0.41) | PPARDPPARAPOLBPPARG | |
| SCHEMBL9979610 | 0.79 | PPARD (0.54) | PPARDPPARAPPARGUGCGSERPINE1 | |
| SCHEMBL9979468 | 0.78 | PPARD (0.45) | PPARDPPARAPPARGUGCG | |
| SCHEMBL9979611 | 0.75 | PPARD (0.46) | PPARDPPARAPPARG | |
| SCHEMBL9979701 | 0.74 | PPARG (0.49) | PPARDPPARAPPARG | |
| SCHEMBL9979660 | 0.72 | PPARD (0.41) | PPARDPPARAMAPTHTTPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012081570-A1 | LACTAM COMPOUND OR A SALT THEREOF, AND PPAR ACTIVATOR | あすか製薬株式会社 (JP) | 2012-06-21 | — | — | WO | disclosed |