Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 10/20 | 0.41 |
| ▸ | PPARG | P37231 | 6/20 | 0.41 |
| ▸ | PPARD | Q03181 | 6/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | LIPE | Q05469 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9979691 | 0.91 | CYP11B1 (0.40) | PPARAPPARGPPARDCYP11B1CYP11B2 | |
| SCHEMBL9979693 | 0.90 | PPARD (0.51) | PPARAPPARGPPARDPLA2G4A | |
| SCHEMBL9979570 | 0.90 | ALDH1A1 (0.38) | PPARAPPARGPPARDCYP11B1CYP11B2 | |
| SCHEMBL9979501 | 0.89 | PPARD (0.47) | PPARAPPARGPPARDCYP11B1CYP11B2 | |
| SCHEMBL9979507 | 0.89 | PPARD (0.47) | PPARAPPARGPPARDCYP11B1CYP11B2 | |
| SCHEMBL9979705 | 0.85 | PPARD (0.42) | PPARAPPARGPPARDCYP11B1CYP11B2 | |
| SCHEMBL9979476 | 0.84 | PPARD (0.50) | PPARAPPARGPPARD | |
| SCHEMBL9979609 | 0.84 | PPARA (0.41) | PPARAPPARGPPARDCYP11B1CYP11B2 | |
| SCHEMBL9979487 | 0.83 | PPARD (0.53) | PPARAPPARGPPARD | |
| SCHEMBL9979485 | 0.82 | PPARD (0.47) | PPARAPPARGPPARDCYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012081570-A1 | LACTAM COMPOUND OR A SALT THEREOF, AND PPAR ACTIVATOR | あすか製薬株式会社 (JP) | 2012-06-21 | — | — | WO | disclosed |