Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 7/20 | 0.36 |
| ▸ | PPARG | P37231 | 6/20 | 0.36 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 2/20 | 0.35 |
| ▸ | PPARD | Q03181 | 5/20 | 0.34 |
| ▸ | UGCG | Q16739 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9979691 | 0.92 | CYP11B1 (0.40) | ALDH1A1GAAPPARAPPARGHSD17B1 | |
| SCHEMBL9979694 | 0.90 | PPARA (0.41) | ALDH1A1GAAPPARAPPARGPPARD | |
| SCHEMBL9979575 | 0.90 | PPARA (0.42) | RAB9ANPC1PKMPPARAPPARG | |
| SCHEMBL9979690 | 0.86 | PPARD (0.43) | PPARAPPARGPPARD | |
| SCHEMBL9979572 | 0.86 | PPARD (0.43) | PPARAPPARGPPARD | |
| SCHEMBL9979673 | 0.82 | RAB9A (0.36) | RAB9AMEN1KMT2ANPC1PKM | |
| SCHEMBL9979519 | 0.82 | FFAR1 (0.43) | RAB9AMEN1KMT2APPARAPPARG | |
| SCHEMBL9979499 | 0.81 | PPARD (0.49) | PPARAPPARGPPARD | |
| SCHEMBL9979502 | 0.80 | PPARD (0.41) | PPARAPPARGHSD17B1PPARD | |
| SCHEMBL9979512 | 0.80 | PPARD (0.41) | PPARAPPARGCASP3PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012081570-A1 | LACTAM COMPOUND OR A SALT THEREOF, AND PPAR ACTIVATOR | あすか製薬株式会社 (JP) | 2012-06-21 | — | — | WO | disclosed |